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Page 1
Limitations of gene editing assessments in human preimplantation embryos.
Liang D, Mikhalchenko A, Ma H, Marti Gutierrez N, Chen T, Lee Y, Park SW, Tippner-Hedges R, Koski A, Darby H, Li Y, Van Dyken C, Zhao H, Wu K, Zhang J, Hou Z, So S, Han J, Park J, Kim CJ, Zong K, Gong J, Yuan Y, Gu Y, Shen Y, Olson SB, Yang H, Battaglia D, O'Leary T, Krieg SA, Lee DM, Wu DH, Duell PB, Kaul S, Kim JS, Heitner SB, Kang E, Chen ZJ, Amato P, Mitalipov S. Liang D, et al. Among authors: darby h. Nat Commun. 2023 Mar 7;14(1):1219. doi: 10.1038/s41467-023-36820-6. Nat Commun. 2023. PMID: 36882397 Free PMC article.
Correction of a pathogenic gene mutation in human embryos.
Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, Koski A, Ji D, Hayama T, Ahmed R, Darby H, Van Dyken C, Li Y, Kang E, Park AR, Kim D, Kim ST, Gong J, Gu Y, Xu X, Battaglia D, Krieg SA, Lee DM, Wu DH, Wolf DP, Heitner SB, Belmonte JCI, Amato P, Kim JS, Kaul S, Mitalipov S. Ma H, et al. Among authors: darby h. Nature. 2017 Aug 24;548(7668):413-419. doi: 10.1038/nature23305. Epub 2017 Aug 2. Nature. 2017. PMID: 28783728
Ma et al. reply.
Ma H, Marti-Gutierrez N, Park SW, Wu J, Hayama T, Darby H, Van Dyken C, Li Y, Koski A, Liang D, Suzuki K, Gu Y, Gong J, Xu X, Ahmed R, Lee Y, Kang E, Ji D, Park AR, Kim D, Kim ST, Heitner SB, Battaglia D, Krieg SA, Lee DM, Wu DH, Wolf DP, Amato P, Kaul S, Belmonte JCI, Kim JS, Mitalipov S. Ma H, et al. Among authors: darby h. Nature. 2018 Aug;560(7717):E10-E23. doi: 10.1038/s41586-018-0381-y. Nature. 2018. PMID: 30089923 No abstract available.
Deleterious mtDNA mutations are common in mature oocytes.
Ma H, Hayama T, Van Dyken C, Darby H, Koski A, Lee Y, Gutierrez NM, Yamada S, Li Y, Andrews M, Ahmed R, Liang D, Gonmanee T, Kang E, Nasser M, Kempton B, Brigande J, McGill TJ, Terzic A, Amato P, Mitalipov S. Ma H, et al. Among authors: darby h. Biol Reprod. 2020 Mar 13;102(3):607-619. doi: 10.1093/biolre/ioz202. Biol Reprod. 2020. PMID: 31621839 Free PMC article.
Haploidy in somatic cells is induced by mature oocytes in mice.
Lee Y, Trout A, Marti-Gutierrez N, Kang S, Xie P, Mikhalchenko A, Kim B, Choi J, So S, Han J, Xu J, Koski A, Ma H, Yoon JD, Van Dyken C, Darby H, Liang D, Li Y, Tippner-Hedges R, Xu F, Amato P, Palermo GD, Mitalipov S, Kang E. Lee Y, et al. Among authors: darby h. Commun Biol. 2022 Jan 25;5(1):95. doi: 10.1038/s42003-022-03040-5. Commun Biol. 2022. PMID: 35079104 Free PMC article.
Germline and somatic mtDNA mutations in mouse aging.
Ma H, Lee Y, Hayama T, Van Dyken C, Marti-Gutierrez N, Li Y, Ahmed R, Koski A, Kang E, Darby H, Gonmanee T, Park Y, Wolf DP, Jai Kim C, Mitalipov S. Ma H, et al. Among authors: darby h. PLoS One. 2018 Jul 24;13(7):e0201304. doi: 10.1371/journal.pone.0201304. eCollection 2018. PLoS One. 2018. PMID: 30040856 Free PMC article.
Germline transmission of donor, maternal and paternal mtDNA in primates.
Ma H, Van Dyken C, Darby H, Mikhalchenko A, Marti-Gutierrez N, Koski A, Liang D, Li Y, Tippner-Hedges R, Kang E, Lee Y, Sidener H, Ramsey C, Hodge T, Amato P, Mitalipov S. Ma H, et al. Among authors: darby h. Hum Reprod. 2021 Jan 25;36(2):493-505. doi: 10.1093/humrep/deaa308. Hum Reprod. 2021. PMID: 33289786 Free PMC article.
First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility.
Costa-Borges N, Nikitos E, Späth K, Miguel-Escalada I, Ma H, Rink K, Coudereau C, Darby H, Koski A, Van Dyken C, Mestres E, Papakyriakou E, De Ziegler D, Kontopoulos G, Mantzavinos T, Vasilopoulos I, Grigorakis S, Prokopakis T, Dimitropoulos K, Polyzos P, Vlachos N, Kostaras K, Mitalipov S, Calderón G, Psathas P, Wells D. Costa-Borges N, et al. Among authors: darby h. Fertil Steril. 2023 Jun;119(6):964-973. doi: 10.1016/j.fertnstert.2023.02.008. Epub 2023 Feb 12. Fertil Steril. 2023. PMID: 36787873
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Parker CC, Clarke NW, Cook AD, Kynaston H, Catton CN, Cross WR, Petersen PM, Persad RA, Saad F, Bower LC, Logue J, Payne H, Forcat S, Goldstein C, Murphy C, Anderson J, Barkati M, Bottomley DM, Branagan J, Choudhury A, Chung PWM, Cogley L, Goh CL, Hoskin P, Khoo V, Malone SC, Masters L, Morris SL, Nabid A, Ong AD, Raman R, Tarver KL, Tree AC, Worlding J, Wylie JP, Zarkar AM, Parulekar WR, Parmar MKB, Sydes MR; RADICALS investigators. Parker CC, et al. Lancet. 2024 May 16:S0140-6736(24)00548-8. doi: 10.1016/S0140-6736(24)00548-8. Online ahead of print. Lancet. 2024. PMID: 38763154 Free article.
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial.
Parker CC, Kynaston H, Cook AD, Clarke NW, Catton CN, Cross WR, Petersen PM, Persad RA, Pugh CA, Saad F, Logue J, Payne H, Bower LC, Brawley C, Rauchenberger M, Barkati M, Bottomley DM, Brasso K, Chung HT, Chung PWM, Conroy R, Falconer A, Ford V, Goh CL, Heath CM, James ND, Kim-Sing C, Kodavatiganti R, Malone SC, Morris SL, Nabid A, Ong AD, Raman R, Rodda S, Wells P, Worlding J, Parulekar WR, Parmar MKB, Sydes MR; RADICALS investigators. Parker CC, et al. Lancet. 2024 May 16:S0140-6736(24)00549-X. doi: 10.1016/S0140-6736(24)00549-X. Online ahead of print. Lancet. 2024. PMID: 38763153 Free article.
56 results