Damas AM - Search Results

1

Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors.

Mairal T, Nieto J, Pinto M, Almeida MR, Gales L, Ballesteros A, Barluenga J, Pérez JJ, Vázquez JT, Centeno NB, Saraiva MJ, Damas AM, Planas A, Arsequell G, Valencia G. Mairal T, et al. Among authors: damas am. PLoS One. 2009;4(1):e4124. doi: 10.1371/journal.pone.0004124. Epub 2009 Jan 6. PLoS One. 2009. PMID: 19125186 Free PMC article.

2

Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor.

Gales L, Macedo-Ribeiro S, Arsequell G, Valencia G, Saraiva MJ, Damas AM. Gales L, et al. Among authors: damas am. Biochem J. 2005 Jun 1;388(Pt 2):615-21. doi: 10.1042/BJ20042035. Biochem J. 2005. PMID: 15689188 Free PMC article.

3

Iodination of salicylic acid improves its binding to transthyretin.

Gales L, Almeida MR, Arsequell G, Valencia G, Saraiva MJ, Damas AM. Gales L, et al. Among authors: damas am. Biochim Biophys Acta. 2008 Mar;1784(3):512-7. doi: 10.1016/j.bbapap.2007.11.014. Epub 2007 Dec 3. Biochim Biophys Acta. 2008. PMID: 18155178

4

Structural basis for the protective role of sulfite against transthyretin amyloid formation.

Gales L, Saraiva MJ, Damas AM. Gales L, et al. Among authors: damas am. Biochim Biophys Acta. 2007 Jan;1774(1):59-64. doi: 10.1016/j.bbapap.2006.10.015. Epub 2006 Nov 6. Biochim Biophys Acta. 2007. PMID: 17175208

5

The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.

Morais-de-Sá E, Pereira PJ, Saraiva MJ, Damas AM. Morais-de-Sá E, et al. Among authors: damas am. J Biol Chem. 2004 Dec 17;279(51):53483-90. doi: 10.1074/jbc.M408053200. Epub 2004 Oct 6. J Biol Chem. 2004. PMID: 15469931 Free article.

6

Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils.

Castro-Rodrigues AF, Gales L, Saraiva MJ, Damas AM. Castro-Rodrigues AF, et al. Among authors: damas am. Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1035-44. doi: 10.1107/S090744491104491X. Epub 2011 Nov 5. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 22120741

7

Designing transthyretin mutants affecting tetrameric structure: implications in amyloidogenicity.

Redondo C, Damas AM, Saraiva MJ. Redondo C, et al. Among authors: damas am. Biochem J. 2000 May 15;348 Pt 1(Pt 1):167-72. Biochem J. 2000. PMID: 10794728 Free PMC article.

8

Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.

Almeida MR, Gales L, Damas AM, Cardoso I, Saraiva MJ. Almeida MR, et al. Among authors: damas am. Curr Drug Targets CNS Neurol Disord. 2005 Oct;4(5):587-96. doi: 10.2174/156800705774322076. Curr Drug Targets CNS Neurol Disord. 2005. PMID: 16266291 Review.

9

The binding of xanthone derivatives to transthyretin.

Maia F, Almeida Mdo R, Gales L, Kijjoa A, Pinto MM, Saraiva MJ, Damas AM. Maia F, et al. Among authors: damas am. Biochem Pharmacol. 2005 Dec 5;70(12):1861-9. doi: 10.1016/j.bcp.2005.09.012. Epub 2005 Oct 19. Biochem Pharmacol. 2005. PMID: 16236271

10

Distinct annular oligomers captured along the assembly and disassembly pathways of transthyretin amyloid protofibrils.

Pires RH, Karsai Á, Saraiva MJ, Damas AM, Kellermayer MS. Pires RH, et al. Among authors: damas am. PLoS One. 2012;7(9):e44992. doi: 10.1371/journal.pone.0044992. Epub 2012 Sep 12. PLoS One. 2012. PMID: 22984597 Free PMC article.

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