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Host-Guest Interactions between Candesartan and Its Prodrug Candesartan Cilexetil in Complex with 2-Hydroxypropyl-β-cyclodextrin: On the Biological Potency for Angiotensin II Antagonism.
Ntountaniotis D, Andreadelis I, Kellici TF, Karageorgos V, Leonis G, Christodoulou E, Kiriakidi S, Becker-Baldus J, Stylos EK, Chatziathanasiadou MV, Chatzigiannis CM, Damalas DE, Aksoydan B, Javornik U, Valsami G, Glaubitz C, Durdagi S, Thomaidis NS, Kolocouris A, Plavec J, Tzakos AG, Liapakis G, Mavromoustakos T. Ntountaniotis D, et al. Among authors: damalas de. Mol Pharm. 2019 Mar 4;16(3):1255-1271. doi: 10.1021/acs.molpharmaceut.8b01212. Epub 2019 Feb 13. Mol Pharm. 2019. PMID: 30681344
Wide-scope target screening of >2000 emerging contaminants in wastewater samples with UPLC-Q-ToF-HRMS/MS and smart evaluation of its performance through the validation of 195 selected representative analytes.
Gago-Ferrero P, Bletsou AA, Damalas DE, Aalizadeh R, Alygizakis NA, Singer HP, Hollender J, Thomaidis NS. Gago-Ferrero P, et al. Among authors: damalas de. J Hazard Mater. 2020 Apr 5;387:121712. doi: 10.1016/j.jhazmat.2019.121712. Epub 2019 Nov 18. J Hazard Mater. 2020. PMID: 31784138 Free article.
Antihypertensive activity and molecular interactions of irbesartan in complex with 2-hydroxypropyl-β-cyclodextrin.
Leonis G, Christodoulou E, Ntountaniotis D, Chatziathanasiadou MV, Mavromoustakos T, Naziris N, Chountoulesi M, Demetzos C, Valsami G, Damalas DE, Tzakos AG, Thomaidis NS, Karageorgos V, Liapakis G. Leonis G, et al. Among authors: damalas de. Chem Biol Drug Des. 2020 Jul;96(1):668-683. doi: 10.1111/cbdd.13664. Chem Biol Drug Des. 2020. PMID: 32691965
Heart rate as an early warning parameter and proxy for subsequent mortality in Danio rerio embryos exposed to ionisable substances.
Schweizer M, von der Ohe PC, Gräff T, Kühnen U, Hebel J, Heid C, Kundy L, Kuttler J, Moroff FM, Schlösinger AF, Schulze-Berge P, Triebskorn R, Panagopoulou E, Damalas DE, Thomaidis NS, Köhler HR. Schweizer M, et al. Among authors: damalas de. Sci Total Environ. 2022 Apr 20;818:151744. doi: 10.1016/j.scitotenv.2021.151744. Epub 2021 Nov 19. Sci Total Environ. 2022. PMID: 34808159 Free article.
LogD-based modelling and ΔlogD as a proxy for pH-dependent action of ionizable chemicals reveal the relevance of both neutral and ionic species for fish embryotoxicity and possess great potential for practical application in the regulation of chemicals.
Köhler HR, Gräff T, Schweizer M, Blumhardt J, Burkhardt J, Ehmann L, Hebel J, Heid C, Kundy L, Kuttler J, Malusova M, Moroff FM, Schlösinger AF, Schulze-Berge P, Panagopoulou EI, Damalas DE, Thomaidis NS, Triebskorn R, Maletzki D, Kühnen U, von der Ohe PC. Köhler HR, et al. Among authors: damalas de. Water Res. 2023 May 15;235:119864. doi: 10.1016/j.watres.2023.119864. Epub 2023 Mar 14. Water Res. 2023. PMID: 36944304 Free article.
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