Dai X - Search Results

1

Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: dai x. Nature. 2018 Jan 4;553(7686):91-95. doi: 10.1038/nature25015. Epub 2017 Nov 16. Nature. 2018. PMID: 29160310 Free PMC article.

2

Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6.

Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, North BJ, Huo J, Zhang J. Tan Y, et al. Among authors: dai x. Oncotarget. 2017 Jul 18;8(29):47890-47901. doi: 10.18632/oncotarget.18141. Oncotarget. 2017. PMID: 28599312 Free PMC article.

3

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, Buckley DL, Qi J, Buser L, Liu P, Inuzuka H, Beck AH, Wang L, Wild PJ, Garraway LA, Rubin MA, Barbieri CE, Wong KK, Muthuswamy SK, Huang J, Chen Y, Bradner JE, Wei W. Dai X, et al. Nat Med. 2017 Sep;23(9):1063-1071. doi: 10.1038/nm.4378. Epub 2017 Aug 14. Nat Med. 2017. PMID: 28805820 Free PMC article.

4

SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression.

Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, Lu KP, Huang J, Zhao C, Sun Y, Gao X, Pandolfi PP, Wei W. Zhang J, et al. Among authors: dai x. Dev Cell. 2019 Feb 11;48(3):329-344.e5. doi: 10.1016/j.devcel.2018.11.035. Epub 2018 Dec 27. Dev Cell. 2019. PMID: 30595538 Free PMC article.

5

Author Correction: Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: dai x. Nature. 2019 Jul;571(7766):E10. doi: 10.1038/s41586-019-1351-8. Nature. 2019. PMID: 31270456

6

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Among authors: dai x. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

7

SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation.

Wang Z, Dai X, Zhong J, Inuzuka H, Wan L, Li X, Wang L, Ye X, Sun L, Gao D, Zou L, Wei W. Wang Z, et al. Among authors: dai x. Nat Commun. 2015 Dec 15;6:10185. doi: 10.1038/ncomms10185. Nat Commun. 2015. PMID: 26666832 Free PMC article.

8

Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.

Wu F, Dai X, Gan W, Wan L, Li M, Mitsiades N, Wei W, Ding Q, Zhang J. Wu F, et al. Among authors: dai x. Cancer Lett. 2017 Jan 28;385:207-214. doi: 10.1016/j.canlet.2016.10.021. Epub 2016 Oct 22. Cancer Lett. 2017. PMID: 27780719 Free PMC article.

9

Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells.

Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, Hu G, Guo J. Zhang L, et al. Among authors: dai x. Cancer Lett. 2017 Apr 1;390:11-20. doi: 10.1016/j.canlet.2017.01.003. Epub 2017 Jan 13. Cancer Lett. 2017. PMID: 28089830 Free PMC article.

10

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W. Wang B, et al. Among authors: dai x. Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10. Nature. 2017. PMID: 28489822 Free PMC article.

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