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A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies.
Gürgen D, Becker M, Dahlmann M, Flechsig S, Schaeffeler E, Büttner FA, Schmees C, Bohnert R, Bedke J, Schwab M, Wendler JJ, Schostak M, Jandrig B, Walther W, Hoffmann J. Gürgen D, et al. Among authors: dahlmann m. Front Oncol. 2022 Jun 21;12:889789. doi: 10.3389/fonc.2022.889789. eCollection 2022. Front Oncol. 2022. PMID: 35800063 Free PMC article.
MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari F, Dahlmann M, Sporbert A, Mattioli CC, Mari T, Scholz F, Timm L, Twamley S, Migotti R, Walther W, Dittmar G, Rehm A, Stein U. Imbastari F, et al. Among authors: dahlmann m. Cell Mol Life Sci. 2021 Apr;78(7):3525-3542. doi: 10.1007/s00018-020-03734-1. Epub 2021 Jan 20. Cell Mol Life Sci. 2021. PMID: 33469705 Free PMC article.
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt D, Perez-Hernandez D, Fleuter C, Dahlmann M, Zincke F, Smith J, Migotti R, Popp O, Burock S, Walther W, Dittmar G, Mertins P, Stein U. Kobelt D, et al. Among authors: dahlmann m. Oncogene. 2021 Aug;40(34):5286-5301. doi: 10.1038/s41388-021-01917-z. Epub 2021 Jul 10. Oncogene. 2021. PMID: 34247190 Free PMC article.
35 results