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Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Cell Genom. 2023 Oct 27;3(12):100426. doi: 10.1016/j.xgen.2023.100426. eCollection 2023 Dec 13.
Cell Genom. 2023.
PMID: 38116120
Free PMC article.
A guide to epigenetics in leukaemia stem cells.
Agrawal-Singh S, Bagri J, Sakakini N, Huntly BJP.
Agrawal-Singh S, et al.
Mol Oncol. 2023 Dec;17(12):2493-2506. doi: 10.1002/1878-0261.13544. Epub 2023 Nov 2.
Mol Oncol. 2023.
PMID: 37872885
Free PMC article.
Review.
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Distinct and targetable role of calcium-sensing receptor in leukaemia.
Pereira RS, Kumar R, Cais A, Paulini L, Kahler A, Bravo J, Minciacchi VR, Krack T, Kowarz E, Zanetti C, Godavarthy PS, Hoeller F, Llavona P, Stark T, Tascher G, Nowak D, Meduri E, Huntly BJP, Münch C, Pampaloni F, Marschalek R, Krause DS.
Pereira RS, et al.
Nat Commun. 2023 Oct 6;14(1):6242. doi: 10.1038/s41467-023-41770-0.
Nat Commun. 2023.
PMID: 37802982
Free PMC article.
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In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis.
Lara-Astiaso D, Goñi-Salaverri A, Mendieta-Esteban J, Narayan N, Del Valle C, Gross T, Giotopoulos G, Beinortas T, Navarro-Alonso M, Aguado-Alvaro LP, Zazpe J, Marchese F, Torrea N, Calvo IA, Lopez CK, Alignani D, Lopez A, Saez B, Taylor-King JP, Prosper F, Fortelny N, Huntly BJP.
Lara-Astiaso D, et al.
Nat Genet. 2023 Sep;55(9):1542-1554. doi: 10.1038/s41588-023-01471-2. Epub 2023 Aug 14.
Nat Genet. 2023.
PMID: 37580596
Free PMC article.
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HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Agrawal-Singh S, Bagri J, Giotopoulos G, Azazi DMA, Horton SJ, Lopez CK, Anand S, Bach AS, Stedham F, Antrobus R, Houghton JW, Vassiliou GS, Sasca D, Yun H, Whetton AD, Huntly BJP.
Agrawal-Singh S, et al.
Blood. 2023 Apr 6;141(14):1737-1754. doi: 10.1182/blood.2022016528.
Blood. 2023.
PMID: 36577137
Free PMC article.
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