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Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire.
Ou T, He W, Quinlan BD, Guo Y, Tran MH, Karunadharma P, Park H, Davis-Gardner ME, Yin Y, Zhang X, Wang H, Zhong G, Farzan M. Ou T, et al. Mol Ther. 2022 Jan 5;30(1):184-197. doi: 10.1016/j.ymthe.2021.10.027. Epub 2021 Nov 2. Mol Ther. 2022. PMID: 34740791 Free PMC article.
A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020.
Tran MH, Park H, Nobles CL, Karunadharma P, Pan L, Zhong G, Wang H, He W, Ou T, Crynen G, Sheptack K, Stiskin I, Mou H, Farzan M. Tran MH, et al. Mol Ther Nucleic Acids. 2021 Feb 18;24:40-53. doi: 10.1016/j.omtn.2021.02.012. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33738137 Free PMC article.