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Year Number of Results
2020 4
2021 4
2022 1
2023 2
2024 1

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Page 1
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744
A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes.
Bousbaine D, Fisch LI, London M, Bhagchandani P, Rezende de Castro TB, Mimee M, Olesen S, Reis BS, VanInsberghe D, Bortolatto J, Poyet M, Cheloha RW, Sidney J, Ling J, Gupta A, Lu TK, Sette A, Alm EJ, Moon JJ, Victora GD, Mucida D, Ploegh HL, Bilate AM. Bousbaine D, et al. Science. 2022 Aug 5;377(6606):660-666. doi: 10.1126/science.abg5645. Epub 2022 Aug 4. Science. 2022. PMID: 35926021 Free PMC article.
A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants.
Pishesha N, Harmand TJ, Rothlauf PW, Praest P, Alexander RK, van den Doel R, Liebeskind MJ, Vakaki MA, McCaul N, Wijne C, Verhaar E, Pinney W 3rd, Heston H, Bloyet LM, Pontelli MC, Ilagan MXG, Jan Lebbink R, Buchser WJ, Wiertz EJHJ, Whelan SPJ, Ploegh HL. Pishesha N, et al. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2116147118. doi: 10.1073/pnas.2116147118. Proc Natl Acad Sci U S A. 2021. PMID: 34654739 Free PMC article.
Nanobodies in cancer.
Verhaar ER, Woodham AW, Ploegh HL. Verhaar ER, et al. Semin Immunol. 2021 Feb;52:101425. doi: 10.1016/j.smim.2020.101425. Epub 2020 Nov 30. Semin Immunol. 2021. PMID: 33272897 Free PMC article. Review.
Exploring cellular biochemistry with nanobodies.
Cheloha RW, Harmand TJ, Wijne C, Schwartz TU, Ploegh HL. Cheloha RW, et al. J Biol Chem. 2020 Nov 6;295(45):15307-15327. doi: 10.1074/jbc.REV120.012960. Epub 2020 Aug 31. J Biol Chem. 2020. PMID: 32868455 Free PMC article. Review.
11 results