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Targetting PED/PEA-15 for diabetes treatment.
Fiory F, Spinelli R, Raciti GA, Parrillo L, D'esposito V, Formisano P, Miele C, Beguinot F. Fiory F, et al. Expert Opin Ther Targets. 2017 Jun;21(6):571-581. doi: 10.1080/14728222.2017.1317749. Epub 2017 Apr 21. Expert Opin Ther Targets. 2017. PMID: 28395542 Review.
Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death.
Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P. Alberobello AT, et al. J Biol Chem. 2010 Feb 26;285(9):6563-72. doi: 10.1074/jbc.M109.097410. Epub 2009 Dec 31. J Biol Chem. 2010. PMID: 20044479 Free PMC article.
Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo.
Nigro C, Raciti GA, Leone A, Fleming TH, Longo M, Prevenzano I, Fiory F, Mirra P, D'Esposito V, Ulianich L, Nawroth PP, Formisano P, Beguinot F, Miele C. Nigro C, et al. Diabetologia. 2014 Jul;57(7):1485-94. doi: 10.1007/s00125-014-3243-7. Epub 2014 Apr 24. Diabetologia. 2014. PMID: 24759959
63 results