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Page 1
Integration of urban science and urban climate adaptation research: opportunities to advance climate action.
Lobo J, Aggarwal RM, Alberti M, Allen-Dumas M, Bettencourt LMA, Boone C, Brelsford C, Broto VC, Eakin H, Bagchi-Sen S, Meerow S, D'Cruz C, Revi A, Roberts DC, Smith ME, York A, Lin T, Bai X, Solecki W, Pataki D, Tapia LB, Rockman M, Wolfram M, Schlosser P, Gauthier N. Lobo J, et al. Among authors: d cruz c. NPJ Urban Sustain. 2023;3(1):32. doi: 10.1038/s42949-023-00113-0. Epub 2023 Jun 10. NPJ Urban Sustain. 2023. PMID: 37323541 Free PMC article. Review.
A pharmacokinetic-pharmacodynamic model for the MET tyrosine kinase inhibitor, savolitinib, to explore target inhibition requirements for anti-tumour activity.
Jones RDO, Grondine M, Borodovsky A, San Martin M, DuPont M, D'Cruz C, Schuller A, Henry R, Barry E, Castriotta L, Anjum R, Petersson K, Sahota T, Ahmed GF. Jones RDO, et al. Among authors: d cruz c. Br J Pharmacol. 2021 Feb;178(3):600-613. doi: 10.1111/bph.15301. Epub 2020 Dec 7. Br J Pharmacol. 2021. PMID: 33125717 Free article.
Generation of stable PDX derived cell lines using conditional reprogramming.
Borodovsky A, McQuiston TJ, Stetson D, Ahmed A, Whitston D, Zhang J, Grondine M, Lawson D, Challberg SS, Zinda M, Pollok BA, Dougherty BA, D'Cruz CM. Borodovsky A, et al. Among authors: d cruz cm. Mol Cancer. 2017 Dec 6;16(1):177. doi: 10.1186/s12943-017-0745-1. Mol Cancer. 2017. PMID: 29212548 Free PMC article.
Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations.
Ladd B, Mazzola AM, Bihani T, Lai Z, Bradford J, Collins M, Barry E, Goeppert AU, Weir HM, Hearne K, Renshaw JG, Mohseni M, Hurt E, Jalla S, Bao H, Hollingsworth R, Reimer C, Zinda M, Fawell S, D'Cruz CM. Ladd B, et al. Among authors: d cruz cm. Oncotarget. 2016 Aug 23;7(34):54120-54136. doi: 10.18632/oncotarget.10852. Oncotarget. 2016. PMID: 27472462 Free PMC article.
Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation.
Henry RE, Barry ER, Castriotta L, Ladd B, Markovets A, Beran G, Ren Y, Zhou F, Adam A, Zinda M, Reimer C, Qing W, Su W, Clark E, D'Cruz CM, Schuller AG. Henry RE, et al. Among authors: d cruz cm. Oncotarget. 2016 Sep 6;7(36):57651-57670. doi: 10.18632/oncotarget.10859. Oncotarget. 2016. PMID: 27472392 Free PMC article.
AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.
Weir HM, Bradbury RH, Lawson M, Rabow AA, Buttar D, Callis RJ, Curwen JO, de Almeida C, Ballard P, Hulse M, Donald CS, Feron LJ, Karoutchi G, MacFaul P, Moss T, Norman RA, Pearson SE, Tonge M, Davies G, Walker GE, Wilson Z, Rowlinson R, Powell S, Sadler C, Richmond G, Ladd B, Pazolli E, Mazzola AM, D'Cruz C, De Savi C. Weir HM, et al. Among authors: d cruz c. Cancer Res. 2016 Jun 1;76(11):3307-18. doi: 10.1158/0008-5472.CAN-15-2357. Epub 2016 Mar 28. Cancer Res. 2016. PMID: 27020862
51 results