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Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells.
Reprod Toxicol. 2022 Sep;112:36-50. doi: 10.1016/j.reprotox.2022.06.003. Epub 2022 Jun 11.
Reprod Toxicol. 2022.
PMID: 35697279
Hemin-Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition in the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis.
Gonzales J, Holbert K, Czysz K, George J, Fernandes C, Fraidenburg DR.
Gonzales J, et al. Among authors: czysz k.
Int J Mol Sci. 2022 Apr 26;23(9):4763. doi: 10.3390/ijms23094763.
Int J Mol Sci. 2022.
PMID: 35563154
Free PMC article.
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iPSC-derived hepatocytes generated from NASH donors provide a valuable platform for disease modeling and drug discovery.
Gurevich I, Burton SA, Munn C, Ohshima M, Goedland ME, Czysz K, Rajesh D.
Gurevich I, et al. Among authors: czysz k.
Biol Open. 2020 Dec 16;9(12):bio055087. doi: 10.1242/bio.055087.
Biol Open. 2020.
PMID: 33268331
Free PMC article.
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Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Gintant G, Kaushik EP, Feaster T, Stoelzle-Feix S, Kanda Y, Osada T, Smith G, Czysz K, Kettenhofen R, Lu HR, Cai B, Shi H, Herron TJ, Dang Q, Burton F, Pang L, Traebert M, Abassi Y, Pierson JB, Blinova K.
Gintant G, et al. Among authors: czysz k.
Regul Toxicol Pharmacol. 2020 Nov;117:104756. doi: 10.1016/j.yrtph.2020.104756. Epub 2020 Aug 19.
Regul Toxicol Pharmacol. 2020.
PMID: 32822771
Free article.
Review.
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Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Huang KW, Reebye V, Czysz K, Ciriello S, Dorman S, Reccia I, Lai HS, Peng L, Kostomitsopoulos N, Nicholls J, Habib RS, Tomalia DA, Sætrom P, Wilkes E, Cutillas P, Rossi JJ, Habib NA.
Huang KW, et al. Among authors: czysz k.
Mol Ther Nucleic Acids. 2020 Mar 6;19:361-370. doi: 10.1016/j.omtn.2019.10.044. Epub 2019 Nov 21.
Mol Ther Nucleic Acids. 2020.
PMID: 31877412
Free PMC article.
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Translational Prospects and Challenges in Human Induced Pluripotent Stem Cell Research in Drug Discovery.
Hosoya M, Czysz K.
Hosoya M, et al. Among authors: czysz k.
Cells. 2016 Dec 21;5(4):46. doi: 10.3390/cells5040046.
Cells. 2016.
PMID: 28009813
Free PMC article.
Review.
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DMSO efficiently down regulates pluripotency genes in human embryonic stem cells during definitive endoderm derivation and increases the proficiency of hepatic differentiation.
Czysz K, Minger S, Thomas N.
Czysz K, et al.
PLoS One. 2015 Feb 6;10(2):e0117689. doi: 10.1371/journal.pone.0117689. eCollection 2015.
PLoS One. 2015.
PMID: 25659159
Free PMC article.
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