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Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors.
Mukhopadhyay A, Elattar A, Cerbinskaite A, Wilkinson SJ, Drew Y, Kyle S, Los G, Hostomsky Z, Edmondson RJ, Curtin NJ. Mukhopadhyay A, et al. Among authors: curtin nj. Clin Cancer Res. 2010 Apr 15;16(8):2344-51. doi: 10.1158/1078-0432.CCR-09-2758. Epub 2010 Apr 6. Clin Cancer Res. 2010. PMID: 20371688
Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699.
Daniel RA, Rozanska AL, Mulligan EA, Drew Y, Thomas HD, Castelbuono DJ, Hostomsky Z, Plummer ER, Tweddle DA, Boddy AV, Clifford SC, Curtin NJ. Daniel RA, et al. Among authors: curtin nj. Br J Cancer. 2010 Nov 9;103(10):1588-96. doi: 10.1038/sj.bjc.6605946. Epub 2010 Oct 26. Br J Cancer. 2010. PMID: 20978505 Free PMC article.
Defective homologous recombination in human cancers.
Cerbinskaite A, Mukhopadhyay A, Plummer ER, Curtin NJ, Edmondson RJ. Cerbinskaite A, et al. Among authors: curtin nj. Cancer Treat Rev. 2012 Apr;38(2):89-100. doi: 10.1016/j.ctrv.2011.04.015. Epub 2011 Jun 28. Cancer Treat Rev. 2012. PMID: 21715099 Review.
Clinicopathological features of homologous recombination-deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum, and survival.
Mukhopadhyay A, Plummer ER, Elattar A, Soohoo S, Uzir B, Quinn JE, McCluggage WG, Maxwell P, Aneke H, Curtin NJ, Edmondson RJ. Mukhopadhyay A, et al. Among authors: curtin nj. Cancer Res. 2012 Nov 15;72(22):5675-82. doi: 10.1158/0008-5472.CAN-12-0324. Epub 2012 Oct 11. Cancer Res. 2012. PMID: 23066035 Clinical Trial.
The use of ovarian cancer cells from patients undergoing surgery to generate primary cultures capable of undergoing functional analysis.
O Donnell RL, McCormick A, Mukhopadhyay A, Woodhouse LC, Moat M, Grundy A, Dixon M, Kaufman A, Soohoo S, Elattar A, Curtin NJ, Edmondson RJ. O Donnell RL, et al. Among authors: curtin nj. PLoS One. 2014 Mar 6;9(6):e90604. doi: 10.1371/journal.pone.0090604. eCollection 2014. PLoS One. 2014. PMID: 24603616 Free PMC article.
179 results