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Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene.
Romagnoli R, Baraldi PG, IJzerman AP, Massink A, Cruz-Lopez O, Lopez-Cara LC, Saponaro G, Preti D, Aghazadeh Tabrizi M, Baraldi S, Moorman AR, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. J Med Chem. 2014 Sep 25;57(18):7673-86. doi: 10.1021/jm5008853. Epub 2014 Sep 12. J Med Chem. 2014. PMID: 25181013
Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Moorman AR, Massink A, IJzerman AP, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: cruz lopez o. Eur J Med Chem. 2015 Aug 28;101:185-204. doi: 10.1016/j.ejmech.2015.06.041. Epub 2015 Jun 24. Eur J Med Chem. 2015. PMID: 26141910
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E. Romagnoli R, et al. J Med Chem. 2008 Mar 13;51(5):1464-8. doi: 10.1021/jm7011547. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260616
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18440234
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Cara CL, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Kandil S, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5041-5. doi: 10.1016/j.bmcl.2008.08.006. Epub 2008 Aug 6. Bioorg Med Chem Lett. 2008. PMID: 18725179 Free PMC article.
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Ilaria L, Saletti R, Brancale A, Hamel E. Romagnoli R, et al. Bioorg Med Chem. 2008 Sep 15;16(18):8419-26. doi: 10.1016/j.bmc.2008.08.029. Epub 2008 Aug 17. Bioorg Med Chem. 2008. PMID: 18755591 Free PMC article.
49 results