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Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists.
Giovannoni MP, Ciciani G, Cilibrizzi A, Crocetti L, Daniele S, Di Cesare Mannelli L, Ghelardini C, Giacomelli C, Guerrini G, Martini C, Trincavelli ML, Vergelli C. Giovannoni MP, et al. Among authors: crocetti l. Eur J Med Chem. 2015 Jan 7;89:32-41. doi: 10.1016/j.ejmech.2014.10.020. Epub 2014 Oct 12. Eur J Med Chem. 2015. PMID: 25462223
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study.
Guerrini G, Ciciani G, Ciattini S, Crocetti L, Daniele S, Martini C, Melani F, Vergelli C, Giovannoni MP. Guerrini G, et al. Among authors: crocetti l. J Enzyme Inhib Med Chem. 2016;31(2):195-204. doi: 10.3109/14756366.2015.1014475. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 25792503
Cinnoline derivatives as human neutrophil elastase inhibitors.
Giovannoni MP, Schepetkin IA, Crocetti L, Ciciani G, Cilibrizzi A, Guerrini G, Khlebnikov AI, Quinn MT, Vergelli C. Giovannoni MP, et al. Among authors: crocetti l. J Enzyme Inhib Med Chem. 2016 Aug;31(4):628-39. doi: 10.3109/14756366.2015.1057718. Epub 2015 Jul 21. J Enzyme Inhib Med Chem. 2016. PMID: 26194018 Free PMC article.
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.
Vergelli C, Schepetkin IA, Ciciani G, Cilibrizzi A, Crocetti L, Giovannoni MP, Guerrini G, Iacovone A, Kirpotina LN, Khlebnikov AI, Ye RD, Quinn MT. Vergelli C, et al. Among authors: crocetti l. Bioorg Med Chem. 2016 Jun 1;24(11):2530-2543. doi: 10.1016/j.bmc.2016.04.019. Epub 2016 Apr 8. Bioorg Med Chem. 2016. PMID: 27134116 Free PMC article.
Identification of a New Pyrazolo[1,5-a]quinazoline Ligand Highly Affine to γ-Aminobutyric Type A (GABAA) Receptor Subtype with Anxiolytic-Like and Antihyperalgesic Activity.
Guerrini G, Ciciani G, Crocetti L, Daniele S, Ghelardini C, Giovannoni MP, Iacovone A, Di Cesare Mannelli L, Martini C, Vergelli C. Guerrini G, et al. Among authors: crocetti l. J Med Chem. 2017 Dec 14;60(23):9691-9702. doi: 10.1021/acs.jmedchem.7b01151. Epub 2017 Nov 22. J Med Chem. 2017. PMID: 29125291
136 results