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Augmenting glycosylation-directed folding pathways enhances the fidelity of HIV Env immunogen production in plants.
Margolin E, Allen JD, Verbeek M, Chapman R, Meyers A, van Diepen M, Ximba P, Motlou T, Moore PL, Woodward J, Strasser R, Crispin M, Williamson AL, Rybicki EP. Margolin E, et al. Among authors: crispin m. Biotechnol Bioeng. 2022 Oct;119(10):2919-2937. doi: 10.1002/bit.28169. Epub 2022 Jul 19. Biotechnol Bioeng. 2022. PMID: 35781691 Free PMC article.
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens AJ, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E, Desaire H, Crispin M, Wilson IA, Sanders RW, Hassell T, Ward AB, Moore JP. Dey AK, et al. Among authors: crispin m. Biotechnol Bioeng. 2018 Apr;115(4):885-899. doi: 10.1002/bit.26498. Epub 2017 Dec 11. Biotechnol Bioeng. 2018. PMID: 29150937 Free PMC article.
Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.
Behrens AJ, Kumar A, Medina-Ramirez M, Cupo A, Marshall K, Cruz Portillo VM, Harvey DJ, Ozorowski G, Zitzmann N, Wilson IA, Ward AB, Struwe WB, Moore JP, Sanders RW, Crispin M. Behrens AJ, et al. Among authors: crispin m. J Proteome Res. 2018 Mar 2;17(3):987-999. doi: 10.1021/acs.jproteome.7b00639. Epub 2018 Feb 8. J Proteome Res. 2018. PMID: 29420040 Free PMC article.
Structure of the Lassa virus glycan shield provides a model for immunological resistance.
Watanabe Y, Raghwani J, Allen JD, Seabright GE, Li S, Moser F, Huiskonen JT, Strecker T, Bowden TA, Crispin M. Watanabe Y, et al. Among authors: crispin m. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7320-7325. doi: 10.1073/pnas.1803990115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941589 Free PMC article.
Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers.
Aldon Y, McKay PF, Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward AB, Crispin M, Shattock RJ. Aldon Y, et al. Among authors: crispin m. Cell Rep. 2018 Sep 18;24(12):3324-3338.e5. doi: 10.1016/j.celrep.2018.08.051. Cell Rep. 2018. PMID: 30232012 Free PMC article.
227 results