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Multivalent Small-Molecule Pan-RAS Inhibitors.
Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Welsch ME, et al. Among authors: cremers s. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. Cell. 2017. PMID: 28235199 Free PMC article.
Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma.
Jain S, Jirau-Serrano X, Zullo KM, Scotto L, Palermo CF, Sastra SA, Olive KP, Cremers S, Thomas T, Wei Y, Zhang Y, Bhagat G, Amengual JE, Deng C, Karan C, Realubit R, Bates SE, O'Connor OA. Jain S, et al. Among authors: cremers s. Clin Cancer Res. 2015 May 1;21(9):2096-106. doi: 10.1158/1078-0432.CCR-14-2249. Epub 2015 Feb 12. Clin Cancer Res. 2015. PMID: 25677697
Aurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma.
Zullo KM, Guo Y, Cooke L, Jirau-Serrano X, Mangone M, Scotto L, Amengual JE, Mao Y, Nandakumar R, Cremers S, Duong J, Mahadevan D, O'Connor OA. Zullo KM, et al. Among authors: cremers s. Clin Cancer Res. 2015 Sep 15;21(18):4097-109. doi: 10.1158/1078-0432.CCR-15-0033. Epub 2015 Apr 15. Clin Cancer Res. 2015. PMID: 25878331 Free PMC article.
Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.
Amengual JE, Prabhu SA, Lombardo M, Zullo K, Johannet PM, Gonzalez Y, Scotto L, Serrano XJ, Wei Y, Duong J, Nandakumar R, Cremers S, Verma A, Elemento O, O'Connor OA. Amengual JE, et al. Among authors: cremers s. Clin Cancer Res. 2017 Jun 15;23(12):3084-3096. doi: 10.1158/1078-0432.CCR-16-2022. Epub 2016 Dec 19. Clin Cancer Res. 2017. PMID: 27993968 Free PMC article.
A UPLC-MS/MS method for the quantitation of Ulipristal acetate in human serum.
Nandakumar R, Praditpan P, Westhoff CL, Cremers S. Nandakumar R, et al. Among authors: cremers s. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 1;1059:43-48. doi: 10.1016/j.jchromb.2017.05.024. Epub 2017 May 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28570936
Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.
Lue JK, Prabhu SA, Liu Y, Gonzalez Y, Verma A, Mundi PS, Abshiru N, Camarillo JM, Mehta S, Chen EI, Qiao C, Nandakumar R, Cremers S, Kelleher NL, Elemento O, Amengual JE. Lue JK, et al. Among authors: cremers s. Clin Cancer Res. 2019 Sep 1;25(17):5271-5283. doi: 10.1158/1078-0432.CCR-18-3989. Epub 2019 Apr 12. Clin Cancer Res. 2019. PMID: 30979734 Free PMC article.
Aspiration of conjugated bile acids predicts adverse lung transplant outcomes and correlates with airway lipid and cytokine dysregulation.
Urso A, Leiva-Juárez MM, Briganti DF, Aramini B, Benvenuto L, Costa J, Nandakumar R, Gomez EA, Robbins HY, Shah L, Aversa M, Sonnet JR, Arcasoy S, Cremers S, D'Ovidio F. Urso A, et al. Among authors: cremers s. J Heart Lung Transplant. 2021 Sep;40(9):998-1008. doi: 10.1016/j.healun.2021.05.007. Epub 2021 May 28. J Heart Lung Transplant. 2021. PMID: 34183226 Free PMC article.
206 results