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Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
Santini CC, Longden J, Schoof EM, Simpson CD, Jeschke GR, Creixell P, Kim J, Wu X, Turk BE, Rosen N, Poulikakos PI, Linding R. Santini CC, et al. Among authors: creixell p. Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x. Sci Rep. 2019. PMID: 31350469 Free PMC article.
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K. So J, et al. Among authors: creixell p. Sci Signal. 2015 Apr 7;8(371):rs3. doi: 10.1126/scisignal.2005700. Sci Signal. 2015. PMID: 25852190
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.
Creixell P, Schoof EM, Simpson CD, Longden J, Miller CJ, Lou HJ, Perryman L, Cox TR, Zivanovic N, Palmeri A, Wesolowska-Andersen A, Helmer-Citterich M, Ferkinghoff-Borg J, Itamochi H, Bodenmiller B, Erler JT, Turk BE, Linding R. Creixell P, et al. Cell. 2015 Sep 24;163(1):202-17. doi: 10.1016/j.cell.2015.08.056. Epub 2015 Sep 17. Cell. 2015. PMID: 26388441 Free PMC article.
Unmasking determinants of specificity in the human kinome.
Creixell P, Palmeri A, Miller CJ, Lou HJ, Santini CC, Nielsen M, Turk BE, Linding R. Creixell P, et al. Cell. 2015 Sep 24;163(1):187-201. doi: 10.1016/j.cell.2015.08.057. Epub 2015 Sep 17. Cell. 2015. PMID: 26388442 Free PMC article.
Personalized network-based treatments in oncology.
Robin X, Creixell P, Radetskaya O, Santini CC, Longden J, Linding R. Robin X, et al. Among authors: creixell p. Clin Pharmacol Ther. 2013 Dec;94(6):646-50. doi: 10.1038/clpt.2013.171. Epub 2013 Aug 29. Clin Pharmacol Ther. 2013. PMID: 23995267 Review.
Cells, shared memory and breaking the PTM code.
Creixell P, Linding R. Creixell P, et al. Mol Syst Biol. 2012;8:598. doi: 10.1038/msb.2012.33. Mol Syst Biol. 2012. PMID: 22866336 Free PMC article. No abstract available.
18 results