Cragg MS - Search Results

1

Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering.

Yu X, Marshall MJE, Cragg MS, Crispin M. Yu X, et al. Among authors: cragg ms. BioDrugs. 2017 Jun;31(3):151-166. doi: 10.1007/s40259-017-0223-8. BioDrugs. 2017. PMID: 28466278 Review.

2

Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents.

Cragg MS, Glennie MJ. Cragg MS, et al. Blood. 2004 Apr 1;103(7):2738-43. doi: 10.1182/blood-2003-06-2031. Epub 2003 Oct 9. Blood. 2004. PMID: 14551143 Free article.

3

Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation.

Beers SA, Chan CH, James S, French RR, Attfield KE, Brennan CM, Ahuja A, Shlomchik MJ, Cragg MS, Glennie MJ. Beers SA, et al. Among authors: cragg ms. Blood. 2008 Nov 15;112(10):4170-7. doi: 10.1182/blood-2008-04-149161. Epub 2008 Jun 26. Blood. 2008. PMID: 18583569 Free PMC article.

4

Novel antibodies targeting immune regulatory checkpoints for cancer therapy.

Lee CS, Cragg M, Glennie M, Johnson P. Lee CS, et al. Br J Clin Pharmacol. 2013 Aug;76(2):233-47. doi: 10.1111/bcp.12164. Br J Clin Pharmacol. 2013. PMID: 23701301 Free PMC article. Review.

5

Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity.

Vaughan AT, Iriyama C, Beers SA, Chan CH, Lim SH, Williams EL, Shah V, Roghanian A, Frendéus B, Glennie MJ, Cragg MS. Vaughan AT, et al. Among authors: cragg ms. Blood. 2014 Jan 30;123(5):669-77. doi: 10.1182/blood-2013-04-490821. Epub 2013 Nov 13. Blood. 2014. PMID: 24227819 Free article.

6

Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.

Tipton TR, Roghanian A, Oldham RJ, Carter MJ, Cox KL, Mockridge CI, French RR, Dahal LN, Duriez PJ, Hargreaves PG, Cragg MS, Beers SA. Tipton TR, et al. Among authors: cragg ms. Blood. 2015 Mar 19;125(12):1901-9. doi: 10.1182/blood-2014-07-588376. Epub 2015 Jan 28. Blood. 2015. PMID: 25631769 Free article.

7

Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo.

Roghanian A, Teige I, Mårtensson L, Cox KL, Kovacek M, Ljungars A, Mattson J, Sundberg A, Vaughan AT, Shah V, Smyth NR, Sheth B, Chan HT, Li ZC, Williams EL, Manfredi G, Oldham RJ, Mockridge CI, James SA, Dahal LN, Hussain K, Nilsson B, Verbeek JS, Juliusson G, Hansson M, Jerkeman M, Johnson PW, Davies A, Beers SA, Glennie MJ, Frendéus B, Cragg MS. Roghanian A, et al. Among authors: cragg ms. Cancer Cell. 2015 Apr 13;27(4):473-88. doi: 10.1016/j.ccell.2015.03.005. Cancer Cell. 2015. PMID: 25873171 Free article.

8

Antibody modulation: Limiting the efficacy of therapeutic antibodies.

Vaughan AT, Cragg MS, Beers SA. Vaughan AT, et al. Among authors: cragg ms. Pharmacol Res. 2015 Sep;99:269-75. doi: 10.1016/j.phrs.2015.07.003. Epub 2015 Jul 15. Pharmacol Res. 2015. PMID: 26188150

9

Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB.

Stopforth RJ, Cleary KL, Cragg MS. Stopforth RJ, et al. Among authors: cragg ms. J Clin Immunol. 2016 May;36 Suppl 1:88-94. doi: 10.1007/s10875-016-0247-8. Epub 2016 Feb 27. J Clin Immunol. 2016. PMID: 26922075 Free PMC article. Review.

10

Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy.

Li D, Bentley C, Anderson A, Wiblin S, Cleary KLS, Koustoulidou S, Hassanali T, Yates J, Greig J, Nordkamp MO, Trenevska I, Ternette N, Kessler BM, Cornelissen B, Cragg MS, Banham AH. Li D, et al. Among authors: cragg ms. Cancer Res. 2017 May 15;77(10):2699-2711. doi: 10.1158/0008-5472.CAN-16-3247. Epub 2017 Mar 31. Cancer Res. 2017. PMID: 28363997

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