Cowan S - Search Results

1

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.

McCoull W, Cheung T, Anderson E, Barton P, Burgess J, Byth K, Cao Q, Castaldi MP, Chen H, Chiarparin E, Carbajo RJ, Code E, Cowan S, Davey PR, Ferguson AD, Fillery S, Fuller NO, Gao N, Hargreaves D, Howard MR, Hu J, Kawatkar A, Kemmitt PD, Leo E, Molina DM, O'Connell N, Petteruti P, Rasmusson T, Raubo P, Rawlins PB, Ricchiuto P, Robb GR, Schenone M, Waring MJ, Zinda M, Fawell S, Wilson DM. McCoull W, et al. Among authors: cowan s. ACS Chem Biol. 2018 Nov 16;13(11):3131-3141. doi: 10.1021/acschembio.8b00698. Epub 2018 Oct 17. ACS Chem Biol. 2018. PMID: 30335946

2

Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay.

Shaw J, Leveridge M, Norling C, Karén J, Molina DM, O'Neill D, Dowling JE, Davey P, Cowan S, Dabrowski M, Main M, Gianni D. Shaw J, et al. Among authors: cowan s. Sci Rep. 2018 Jan 9;8(1):163. doi: 10.1038/s41598-017-18650-x. Sci Rep. 2018. PMID: 29317749 Free PMC article.

3

Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator.

Frederickson M, Callaghan O, Chessari G, Congreve M, Cowan SR, Matthews JE, McMenamin R, Smith DM, Vinković M, Wallis NG. Frederickson M, et al. J Med Chem. 2008 Jan 24;51(2):183-6. doi: 10.1021/jm701359z. Epub 2007 Dec 29. J Med Chem. 2008. PMID: 18163548

4

Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.

Murray CW, Carr MG, Callaghan O, Chessari G, Congreve M, Cowan S, Coyle JE, Downham R, Figueroa E, Frederickson M, Graham B, McMenamin R, O'Brien MA, Patel S, Phillips TR, Williams G, Woodhead AJ, Woolford AJ. Murray CW, et al. Among authors: cowan s. J Med Chem. 2010 Aug 26;53(16):5942-55. doi: 10.1021/jm100059d. J Med Chem. 2010. PMID: 20718493

5

Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.

Congreve M, Aharony D, Albert J, Callaghan O, Campbell J, Carr RA, Chessari G, Cowan S, Edwards PD, Frederickson M, McMenamin R, Murray CW, Patel S, Wallis N. Congreve M, et al. Among authors: cowan s. J Med Chem. 2007 Mar 22;50(6):1124-32. doi: 10.1021/jm061197u. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315857

6

X-ray Screening of an Electrophilic Fragment Library and Application toward the Development of a Novel ERK 1/2 Covalent Inhibitor.

St Denis JD, Chessari G, Cleasby A, Cons BD, Cowan S, Dalton SE, East C, Murray CW, O'Reilly M, Peakman T, Rapti M, Stow JL. St Denis JD, et al. Among authors: cowan s. J Med Chem. 2022 Sep 22;65(18):12319-12333. doi: 10.1021/acs.jmedchem.2c01044. Epub 2022 Sep 13. J Med Chem. 2022. PMID: 36101934

7

Barriers and enablers to a healthy lifestyle in people with infertility: a mixed-methods systematic review.

Torkel S, Wang R, Norman RJ, Zhao L, Liu K, Boden D, Xu W, Moran L, Cowan S. Torkel S, et al. Among authors: cowan s. Hum Reprod Update. 2024 May 14:dmae011. doi: 10.1093/humupd/dmae011. Online ahead of print. Hum Reprod Update. 2024. PMID: 38743500

8

Antimicrobial-resistant Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance study.

Golparian D, Cole MJ, Sánchez-Busó L, Day M, Jacobsson S, Uthayakumaran T, Abad R, Bercot B, Caugant DA, Heuer D, Jansen K, Pleininger S, Stefanelli P, Aanensen DM, Bluemel B, Unemo M; Euro-GASP study group. Golparian D, et al. Lancet Microbe. 2024 May;5(5):e478-e488. doi: 10.1016/S2666-5247(23)00370-1. Epub 2024 Apr 10. Lancet Microbe. 2024. PMID: 38614111 Free article.

9

Injury prevention for women and girls playing Australian Football: programme cocreation, dissemination and early adopter coach feedback.

Patterson BE, Crossley KM, Haberfield MJ, Mosler AB, Cowan SM, Lawrence J, Rath D, Livingstone N, Barton CJ, Bruder AM, Donaldson A. Patterson BE, et al. Among authors: cowan sm. BMJ Open Sport Exerc Med. 2024 Mar 19;10(1):e001711. doi: 10.1136/bmjsem-2023-001711. eCollection 2024. BMJ Open Sport Exerc Med. 2024. PMID: 38511168 Free PMC article.

10

Translating evidence into practice in primary care management of adolescents and women with polycystic ovary syndrome: a mixed-methods study.

Cowan S, Moran L, Garad R, Sturgiss E, Lim S, Ee C. Cowan S, et al. Fam Pract. 2024 Apr 15;41(2):175-184. doi: 10.1093/fampra/cmae007. Fam Pract. 2024. PMID: 38438311 Free PMC article.

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