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Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A.
Jürjens G, Schuler SMM, Kurz M, Petit S, Couturier C, Jeannot F, Nguyen F, Wende RC, Hammann PE, Wilson DN, Bacqué E, Pöverlein C, Bauer A. Jürjens G, et al. Among authors: couturier c. Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12157-12161. doi: 10.1002/anie.201805901. Epub 2018 Aug 13. Angew Chem Int Ed Engl. 2018. PMID: 30004165
Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin.
Couturier C, Groß S, von Tesmar A, Hoffmann J, Deckarm S, Fievet A, Dubarry N, Taillier T, Pöverlein C, Stump H, Kurz M, Toti L, Haag Richter S, Schummer D, Sizun P, Hoffmann M, Prasad Awal R, Zaburannyi N, Harmrolfs K, Wink J, Lessoud E, Vermat T, Cazals V, Silve S, Bauer A, Mourez M, Fraisse L, Leroi-Geissler C, Rey A, Versluys S, Bacqué E, Müller R, Renard S. Couturier C, et al. Angew Chem Int Ed Engl. 2022 Dec 19;61(51):e202210747. doi: 10.1002/anie.202210747. Epub 2022 Nov 21. Angew Chem Int Ed Engl. 2022. PMID: 36197755 Free PMC article.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, Scarry SM, Aubé J, Yang G, Ouerfelli O, Schnappinger D, Ioerger TR, Engelhart CA, McConnell JA, McAulay K, Fay A, Roubert C, Sacchettini J, Nathan C. Ballinger E, et al. Among authors: couturier c. Science. 2019 Feb 1;363(6426):eaau8959. doi: 10.1126/science.aau8959. Science. 2019. PMID: 30705156 Free PMC article.
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
Lopez Quezada L, Silve S, Kelinske M, Liba A, Diaz Gonzalez C, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S, Bacqué E, Couturier C, Pellet A, Blanc I, Ferron M, Debu F, Li K, Aubé J, Roberts J, Little D, Ling Y, Zhang J, Gold B, Nathan C. Lopez Quezada L, et al. Among authors: couturier c. mBio. 2019 Jul 9;10(4):e01405-19. doi: 10.1128/mBio.01405-19. mBio. 2019. PMID: 31289182 Free PMC article.
Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin.
Renard S, Versluys S, Taillier T, Dubarry N, Leroi-Geissler C, Rey A, Cornaire E, Sordello S, Carry JB, Angouillant-Boniface O, Gouyon T, Thompson F, Lebourg G, Certal V, Balazs L, Arranz E, Doerflinger G, Bretin F, Gervat V, Brohan E, Kraft V, Boulenc X, Ducelier C, Bacqué E, Couturier C. Renard S, et al. Among authors: couturier c. J Med Chem. 2023 Dec 28;66(24):16869-16887. doi: 10.1021/acs.jmedchem.3c01564. Epub 2023 Dec 13. J Med Chem. 2023. PMID: 38088830
Inhibitors of the Neisseria meningitidis PilF ATPase provoke type IV pilus disassembly.
Aubey F, Corre JP, Kong Y, Xu X, Obino D, Goussard S, Lapeyrere C, Souphron J, Couturier C, Renard S, Duménil G. Aubey F, et al. Among authors: couturier c. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8481-8486. doi: 10.1073/pnas.1817757116. Epub 2019 Apr 4. Proc Natl Acad Sci U S A. 2019. PMID: 30948644 Free PMC article.
198 results