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TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment.
Montibus B, Cercy J, Bouschet T, Charras A, Maupetit-Méhouas S, Nury D, Gonthier-Guéret C, Chauveau S, Allegre N, Chariau C, Hong CC, Vaillant I, Marques CJ, Court F, Arnaud P. Montibus B, et al. Among authors: court f. Cell Mol Life Sci. 2021 Jan;78(2):757-768. doi: 10.1007/s00018-020-03541-8. Epub 2020 May 14. Cell Mol Life Sci. 2021. PMID: 32405722 Free PMC article.
Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.
Maupetit-Méhouas S, Montibus B, Nury D, Tayama C, Wassef M, Kota SK, Fogli A, Cerqueira Campos F, Hata K, Feil R, Margueron R, Nakabayashi K, Court F, Arnaud P. Maupetit-Méhouas S, et al. Among authors: court f. Nucleic Acids Res. 2016 Jan 29;44(2):621-35. doi: 10.1093/nar/gkv960. Epub 2015 Sep 22. Nucleic Acids Res. 2016. PMID: 26400168 Free PMC article.
The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients' survival.
Fogli A, Chautard E, Vaurs-Barrière C, Pereira B, Müller-Barthélémy M, Court F, Biau J, Pinto AA, Kémény JL, Khalil T, Karayan-Tapon L, Verrelle P, Costa BM, Arnaud P. Fogli A, et al. Among authors: court f. Carcinogenesis. 2016 Feb;37(2):169-176. doi: 10.1093/carcin/bgv251. Epub 2015 Dec 30. Carcinogenesis. 2016. PMID: 26717998
DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34+ CD15- cells in early chronic-phase chronic myeloid leukemia.
Maupetit-Mehouas S, Court F, Bourgne C, Guerci-Bresler A, Cony-Makhoul P, Johnson H, Etienne G, Rousselot P, Guyotat D, Janel A, Hermet E, Saugues S, Berger J, Arnaud P, Berger MG. Maupetit-Mehouas S, et al. Among authors: court f. Mol Oncol. 2018 Jun;12(6):814-829. doi: 10.1002/1878-0261.12191. Epub 2018 Apr 27. Mol Oncol. 2018. PMID: 29575763 Free PMC article.
High-salt-recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies.
Baudement MO, Cournac A, Court F, Seveno M, Parrinello H, Reynes C, Sabatier R, Bouschet T, Yi Z, Sallis S, Tancelin M, Rebouissou C, Cathala G, Lesne A, Mozziconacci J, Journot L, Forné T. Baudement MO, et al. Among authors: court f. Genome Res. 2018 Nov;28(11):1733-1746. doi: 10.1101/gr.237073.118. Epub 2018 Oct 4. Genome Res. 2018. PMID: 30287550 Free PMC article.
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage.
Le Boiteux E, Court F, Guichet PO, Vaurs-Barrière C, Vaillant I, Chautard E, Verrelle P, Costa BM, Karayan-Tapon L, Fogli A, Arnaud P. Le Boiteux E, et al. Among authors: court f. Mol Oncol. 2021 Aug;15(8):1995-2010. doi: 10.1002/1878-0261.12944. Epub 2021 May 2. Mol Oncol. 2021. PMID: 33720519 Free PMC article.
L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus.
Pinson ME, Court F, Masson A, Renaud Y, Fantini A, Bacoeur-Ouzillou O, Barriere M, Pereira B, Guichet PO, Chautard E, Karayan-Tapon L, Verrelle P, Arnaud P, Vaurs-Barrière C. Pinson ME, et al. Among authors: court f. Hum Mol Genet. 2022 Aug 17;31(15):2606-2622. doi: 10.1093/hmg/ddac056. Hum Mol Genet. 2022. PMID: 35298627 Free PMC article.
176 results