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Immunomodulatory Nanoparticles Mitigate Macrophage Inflammation via Inhibition of PAMP Interactions and Lactate-Mediated Functional Reprogramming of NF-κB and p38 MAPK.
Pharmaceutics. 2021 Nov 2;13(11):1841. doi: 10.3390/pharmaceutics13111841.
Pharmaceutics. 2021.
PMID: 34834256
Free PMC article.
Modified Suberoylanilide Hydroxamic Acid Reduced Drug-Associated Immune Cell Death and Organ Damage under Lipopolysaccharide Inflammatory Challenge.
Truong N, Goodis CC, Cottingham AL, Shaw JR, Fletcher S, Pearson RM.
Truong N, et al. Among authors: cottingham al.
ACS Pharmacol Transl Sci. 2022 Oct 10;5(11):1128-1141. doi: 10.1021/acsptsci.2c00119. eCollection 2022 Nov 11.
ACS Pharmacol Transl Sci. 2022.
PMID: 36407956
Free PMC article.
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Lipid-Polymer Hybrid Nanoparticles Utilize B Cells and Dendritic Cells to Elicit Distinct Antigen-Specific CD4+ and CD8+ T Cell Responses.
Zhang MH, Scotland BL, Jiao Y, Slaby EM, Truong N, Cottingham AL, Stephanie G, Szeto GL, Pearson RM.
Zhang MH, et al. Among authors: cottingham al.
ACS Appl Bio Mater. 2023 May 23:10.1021/acsabm.3c00229. doi: 10.1021/acsabm.3c00229. Online ahead of print.
ACS Appl Bio Mater. 2023.
PMID: 37219857
Review.
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Cell and biomaterial delivery strategies to induce immune tolerance.
Scotland BL, Shaw JR, Dharmaraj S, Caprio N, Cottingham AL, Joy Martín Lasola J, Sung JJ, Pearson RM.
Scotland BL, et al. Among authors: cottingham al.
Adv Drug Deliv Rev. 2023 Dec;203:115141. doi: 10.1016/j.addr.2023.115141. Epub 2023 Nov 18.
Adv Drug Deliv Rev. 2023.
PMID: 37980950
Review.
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Multimodal nanoparticle-containing modified suberoylanilide hydroxamic acid polymer conjugates to mitigate immune dysfunction in severe inflammation.
Truong N, Cottingham AL, Dharmaraj S, Shaw JR, Lasola JJM, Goodis CC, Fletcher S, Pearson RM.
Truong N, et al. Among authors: cottingham al.
Bioeng Transl Med. 2023 Oct 14;9(1):e10611. doi: 10.1002/btm2.10611. eCollection 2024 Jan.
Bioeng Transl Med. 2023.
PMID: 38193117
Free PMC article.
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