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Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.
He M, Saeed MB, Record J, Keszei M, Gonçalves Pinho L, Vasconcelos-Fontes L, D'Aulerio R, Vieira R, Oliveira MMS, Geyer C, Bohaumilitzky L, Thiemann M, Deordieva E, Buedts L, Matias Lopes JP, Pershin D, Hammarström L, Xia Y, Zhao X, Cunningham-Rundles C, Thrasher AJ, Burns SO, Cotta-de-Almeida V, Liu C, Shcherbina A, Vandenberghe P, Westerberg LS. He M, et al. Among authors: cotta de almeida v. J Allergy Clin Immunol. 2022 Mar;149(3):1069-1084. doi: 10.1016/j.jaci.2021.07.033. Epub 2021 Aug 9. J Allergy Clin Immunol. 2022. PMID: 34384840 Free article.
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.
Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB. Westerberg LS, et al. J Exp Med. 2010 Jun 7;207(6):1145-52. doi: 10.1084/jem.20091245. Epub 2010 May 31. J Exp Med. 2010. PMID: 20513746 Free PMC article.
Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery.
Oliveira-de-Abreu E, Silva-Dos-Santos D, Lepletier A, Ramos TDP, Ferreira-Reis R, Vasconcelos-Fontes L, Ramos MT, Torres RC, Cotta-de-Almeida V, Carvalho VF, Villa-Verde DMS. Oliveira-de-Abreu E, et al. Front Endocrinol (Lausanne). 2018 Jul 10;9:365. doi: 10.3389/fendo.2018.00365. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30042731 Free PMC article.
54 results