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Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma.
Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. Magill ST, et al. Among authors: costello jf. Nat Commun. 2020 Sep 23;11(1):4803. doi: 10.1038/s41467-020-18582-7. Nat Commun. 2020. PMID: 32968068 Free PMC article.
Regulatory network decoded from epigenomes of surface ectoderm-derived cell types.
Lowdon RF, Zhang B, Bilenky M, Mauro T, Li D, Gascard P, Sigaroudinia M, Farnham PJ, Bastian BC, Tlsty TD, Marra MA, Hirst M, Costello JF, Wang T, Cheng JB. Lowdon RF, et al. Among authors: costello jf. Nat Commun. 2014 Nov 25;5:5442. doi: 10.1038/ncomms6442. Nat Commun. 2014. PMID: 25421844 Free PMC article.
HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth.
Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M, Nguyen V, Wheeler ML, Murphy MP, Sanders TA, Jeffrey SS, Yeghiazarians Y, Rinaudo PF, Costello JF, Aghi MK, Maltepe E. Ameri K, et al. Among authors: costello jf. Cell Rep. 2015 Feb 17;10(6):891-899. doi: 10.1016/j.celrep.2015.01.020. Epub 2015 Feb 13. Cell Rep. 2015. PMID: 25683712 Free PMC article.
Epigenetic and transcriptional determinants of the human breast.
Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, Heravi-Moussavi A, Moksa M, Mingay M, Hussainkhel A, Davis B, Nagarajan RP, Hong C, Echipare L, O'Geen H, Hangauer MJ, Cheng JB, Neel D, Hu D, McManus MT, Moore R, Mungall A, Ma Y, Plettner P, Ziv E, Wang T, Farnham PJ, Jones SJ, Marra MA, Tlsty TD, Costello JF, Hirst M. Gascard P, et al. Among authors: costello jf. Nat Commun. 2015 Feb 18;6:6351. doi: 10.1038/ncomms7351. Nat Commun. 2015. PMID: 25690954 Free PMC article.
Cancer: Oncogene brought into the loop.
Grimmer MR, Costello JF. Grimmer MR, et al. Among authors: costello jf. Nature. 2016 Jan 7;529(7584):34-5. doi: 10.1038/nature16330. Epub 2015 Dec 23. Nature. 2016. PMID: 26700812 Free PMC article.
Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D. Wahl M, et al. Among authors: costello jf. Cancer. 2017 Dec 1;123(23):4631-4639. doi: 10.1002/cncr.30909. Epub 2017 Jul 31. Cancer. 2017. PMID: 28759109 Free PMC article. Clinical Trial.
253 results