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Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection.
Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser AJ, Espinosa JM, Sullivan KD, Goodspeed A, Costello JC, Alder JK, Cañas-Arranz R, García-Sastre A, Benam KH. Thomas SN, et al. Among authors: costello jc. iScience. 2023 Jul 14;26(8):107361. doi: 10.1016/j.isci.2023.107361. eCollection 2023 Aug 18. iScience. 2023. PMID: 37554445 Free PMC article.
GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis.
Agarwal N, Dancik GM, Goodspeed A, Costello JC, Owens C, Duex JE, Theodorescu D. Agarwal N, et al. Among authors: costello jc. Cancer Res. 2016 Sep 1;76(17):5175-85. doi: 10.1158/0008-5472.CAN-16-1099. Epub 2016 Jun 16. Cancer Res. 2016. PMID: 27312530 Free PMC article.
Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG. Andrews FH, et al. Among authors: costello jc. Cell Rep. 2016 Sep 20;16(12):3195-3207. doi: 10.1016/j.celrep.2016.08.050. Cell Rep. 2016. PMID: 27653685 Free PMC article.
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Powers RK, et al. Among authors: costello jc. Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9. Nat Commun. 2019. PMID: 31628327 Free PMC article.
86 results