Costa G - Search Results

1

Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies.

Della Volpe S, Nasti R, Queirolo M, Unver MY, Jumde VK, Dömling A, Vasile F, Potenza D, Ambrosio FA, Costa G, Alcaro S, Zucal C, Provenzani A, Di Giacomo M, Rossi D, Hirsch AKH, Collina S. Della Volpe S, et al. Among authors: costa g. ACS Med Chem Lett. 2019 Jan 21;10(4):615-620. doi: 10.1021/acsmedchemlett.8b00600. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996806 Free PMC article.

2

Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.

Alcaro S, Artese A, Costa G, Distinto S, Ortuso F, Parrotta L. Alcaro S, et al. Among authors: costa g. Biochimie. 2011 Aug;93(8):1267-74. doi: 10.1016/j.biochi.2011.06.014. Epub 2011 Jun 16. Biochimie. 2011. PMID: 21699954

3

3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.

Maccioni E, Alcaro S, Cirilli R, Vigo S, Cardia MC, Sanna ML, Meleddu R, Yanez M, Costa G, Casu L, Matyus P, Distinto S. Maccioni E, et al. Among authors: costa g. J Med Chem. 2011 Sep 22;54(18):6394-8. doi: 10.1021/jm2002876. Epub 2011 Aug 17. J Med Chem. 2011. PMID: 21777011

4

New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation.

Varela C, Tavares da Silva EJ, Amaral C, Correia da Silva G, Baptista T, Alcaro S, Costa G, Carvalho RA, Teixeira NA, Roleira FM. Varela C, et al. Among authors: costa g. J Med Chem. 2012 Apr 26;55(8):3992-4002. doi: 10.1021/jm300262w. Epub 2012 Apr 18. J Med Chem. 2012. PMID: 22475216

5

Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches.

Alcaro S, Musetti C, Distinto S, Casatti M, Zagotto G, Artese A, Parrotta L, Moraca F, Costa G, Ortuso F, Maccioni E, Sissi C. Alcaro S, et al. Among authors: costa g. J Med Chem. 2013 Feb 14;56(3):843-55. doi: 10.1021/jm3013486. Epub 2013 Jan 22. J Med Chem. 2013. PMID: 23294188

6

Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data.

Artese A, Costa G, Distinto S, Moraca F, Ortuso F, Parrotta L, Alcaro S. Artese A, et al. Among authors: costa g. Eur J Med Chem. 2013 Oct;68:139-49. doi: 10.1016/j.ejmech.2013.07.022. Epub 2013 Aug 11. Eur J Med Chem. 2013. PMID: 23974014

7

Identification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach.

Artese A, Costa G, Ortuso F, Parrotta L, Alcaro S. Artese A, et al. Among authors: costa g. Molecules. 2013 Sep 30;18(10):12051-70. doi: 10.3390/molecules181012051. Molecules. 2013. PMID: 24084014 Free PMC article.

8

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops.

Sattin G, Artese A, Nadai M, Costa G, Parrotta L, Alcaro S, Palumbo M, Richter SN. Sattin G, et al. Among authors: costa g. PLoS One. 2013 Dec 18;8(12):e84113. doi: 10.1371/journal.pone.0084113. eCollection 2013. PLoS One. 2013. PMID: 24367632 Free PMC article.

9

In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold.

Ortuso F, Amato R, Artese A, D'antona L, Costa G, Talarico C, Gigliotti F, Bianco C, Trapasso F, Schenone S, Musumeci F, Botta L, Perrotti N, Alcaro S. Ortuso F, et al. Among authors: costa g. J Chem Inf Model. 2014 Jul 28;54(7):1828-32. doi: 10.1021/ci500235f. Epub 2014 Jun 13. J Chem Inf Model. 2014. PMID: 24896223

10

New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.

De Monte C, Carradori S, Chimenti P, Secci D, Mannina L, Alcaro F, Petzer A, N'Da CI, Gidaro MC, Costa G, Alcaro S, Petzer JP. De Monte C, et al. Among authors: costa g. Eur J Med Chem. 2014 Jul 23;82:164-71. doi: 10.1016/j.ejmech.2014.05.048. Epub 2014 May 22. Eur J Med Chem. 2014. PMID: 24904963

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