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Mitochondria metabolism sets the species-specific tempo of neuronal development.
Iwata R, Casimir P, Erkol E, Boubakar L, Planque M, Gallego López IM, Ditkowska M, Gaspariunaite V, Beckers S, Remans D, Vints K, Vandekeere A, Poovathingal S, Bird M, Vlaeminck I, Creemers E, Wierda K, Corthout N, Vermeersch P, Carpentier S, Davie K, Mazzone M, Gounko NV, Aerts S, Ghesquière B, Fendt SM, Vanderhaeghen P. Iwata R, et al. Among authors: corthout n. Science. 2023 Feb 10;379(6632):eabn4705. doi: 10.1126/science.abn4705. Epub 2023 Feb 10. Science. 2023. PMID: 36705539
Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, Hardy J, Leroy K, Brion JP, Vanderhaeghen P, De Strooper B. Espuny-Camacho I, et al. Among authors: corthout n. Neuron. 2017 Mar 8;93(5):1066-1081.e8. doi: 10.1016/j.neuron.2017.02.001. Epub 2017 Feb 23. Neuron. 2017. PMID: 28238547 Free article.
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms.
Stoklund Dittlau K, Terrie L, Baatsen P, Kerstens A, De Swert L, Janky R, Corthout N, Masrori P, Van Damme P, Hyttel P, Meyer M, Thorrez L, Freude K, Van Den Bosch L. Stoklund Dittlau K, et al. Among authors: corthout n. Mol Neurodegener. 2023 Jan 18;18(1):5. doi: 10.1186/s13024-022-00591-3. Mol Neurodegener. 2023. PMID: 36653804 Free PMC article.
Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches.
Mesnieres M, Böhm AM, Peredo N, Trompet D, Valle-Tenney R, Bajaj M, Corthout N, Nefyodova E, Cardoen R, Baatsen P, Munck S, Nagy A, Haigh JJ, Khurana S, Verfaillie CM, Maes C. Mesnieres M, et al. Among authors: corthout n. Cell Rep. 2021 Aug 24;36(8):109618. doi: 10.1016/j.celrep.2021.109618. Cell Rep. 2021. PMID: 34433017 Free PMC article.
AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS.
Eykens C, Rossaert E, Duqué S, Rué L, Bento-Abreu A, Hersmus N, Lenaerts A, Kerstens A, Corthout N, Munck S, Van Damme P, Holt MG, von Jonquires G, Klugmann M, Van Den Bosch L, Robberecht W. Eykens C, et al. Among authors: corthout n. Mol Ther Methods Clin Dev. 2021 Jan 20;20:508-519. doi: 10.1016/j.omtm.2021.01.006. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33614825 Free PMC article.
Upregulation of TRPM3 in nociceptors innervating inflamed tissue.
Mulier M, Van Ranst N, Corthout N, Munck S, Vanden Berghe P, Vriens J, Voets T, Moilanen L. Mulier M, et al. Among authors: corthout n. Elife. 2020 Sep 3;9:e61103. doi: 10.7554/eLife.61103. Elife. 2020. PMID: 32880575 Free PMC article.
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