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Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Xiang X, et al. Among authors: corsi gi. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. Nat Commun. 2021. PMID: 34050182 Free PMC article.
Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
Pan X, Qu K, Yuan H, Xiang X, Anthon C, Pashkova L, Liang X, Han P, Corsi GI, Xu F, Liu P, Zhong J, Zhou Y, Ma T, Jiang H, Liu J, Wang J, Jessen N, Bolund L, Yang H, Xu X, Church GM, Gorodkin J, Lin L, Luo Y. Pan X, et al. Among authors: corsi gi. Nat Commun. 2022 Jul 13;13(1):4049. doi: 10.1038/s41467-022-31543-6. Nat Commun. 2022. PMID: 35831290 Free PMC article.
CRISPRon/off: CRISPR/Cas9 on- and off-target gRNA design.
Anthon C, Corsi GI, Gorodkin J. Anthon C, et al. Among authors: corsi gi. Bioinformatics. 2022 Dec 13;38(24):5437-5439. doi: 10.1093/bioinformatics/btac697. Bioinformatics. 2022. PMID: 36271848 Free PMC article.
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.
Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, Aldana BI, Freude K. Haukedal H, et al. Among authors: corsi gi. Brain Behav Immun. 2023 Oct;113:353-373. doi: 10.1016/j.bbi.2023.07.024. Epub 2023 Aug 3. Brain Behav Immun. 2023. PMID: 37543250 Free article.
13 results