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Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen.
Kuzikov M, Costanzi E, Reinshagen J, Esposito F, Vangeel L, Wolf M, Ellinger B, Claussen C, Geisslinger G, Corona A, Iaconis D, Talarico C, Manelfi C, Cannalire R, Rossetti G, Gossen J, Albani S, Musiani F, Herzog K, Ye Y, Giabbai B, Demitri N, Jochmans D, Jonghe S, Rymenants J, Summa V, Tramontano E, Beccari AR, Leyssen P, Storici P, Neyts J, Gribbon P, Zaliani A. Kuzikov M, et al. Among authors: corona a. ACS Pharmacol Transl Sci. 2021 Mar 11;4(3):1096-1110. doi: 10.1021/acsptsci.0c00216. eCollection 2021 Jun 11. ACS Pharmacol Transl Sci. 2021. PMID: 35287429 Free PMC article.
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.
Esposito F, Kharlamova T, Distinto S, Zinzula L, Cheng YC, Dutschman G, Floris G, Markt P, Corona A, Tramontano E. Esposito F, et al. Among authors: corona a. FEBS J. 2011 May;278(9):1444-57. doi: 10.1111/j.1742-4658.2011.08057.x. Epub 2011 Mar 16. FEBS J. 2011. PMID: 21348941 Free PMC article.
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities.
Esposito F, Sanna C, Del Vecchio C, Cannas V, Venditti A, Corona A, Bianco A, Serrilli AM, Guarcini L, Parolin C, Ballero M, Tramontano E. Esposito F, et al. Among authors: corona a. Pathog Dis. 2013 Aug;68(3):116-24. doi: 10.1111/2049-632X.12051. Epub 2013 Jul 2. Pathog Dis. 2013. PMID: 23821410
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R, Cannas V, Distinto S, Sarais G, Del Vecchio C, Esposito F, Bianco G, Corona A, Cottiglia F, Alcaro S, Parolin C, Artese A, Scalise D, Fresta M, Arridu A, Ortuso F, Maccioni E, Tramontano E. Meleddu R, et al. Among authors: corona a. ChemMedChem. 2014 Aug;9(8):1869-79. doi: 10.1002/cmdc.201402015. Epub 2014 May 21. ChemMedChem. 2014. PMID: 24850787
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors.
Carcelli M, Rogolino D, Sechi M, Rispoli G, Fisicaro E, Compari C, Grandi N, Corona A, Tramontano E, Pannecouque C, Naesens L. Carcelli M, et al. Among authors: corona a. Eur J Med Chem. 2014 Aug 18;83:594-600. doi: 10.1016/j.ejmech.2014.06.055. Epub 2014 Jun 26. Eur J Med Chem. 2014. PMID: 24996145
330 results