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A Rapamycin-Activated Caspase 9-Based Suicide Gene.
Stavrou M, Philip B, Traynor-White C, Davis CG, Onuoha S, Cordoba S, Thomas S, Pule M. Stavrou M, et al. Among authors: cordoba s. Mol Ther. 2018 May 2;26(5):1266-1276. doi: 10.1016/j.ymthe.2018.03.001. Epub 2018 Mar 9. Mol Ther. 2018. PMID: 29661681 Free PMC article.
CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial.
Cordoba S, Onuoha S, Thomas S, Pignataro DS, Hough R, Ghorashian S, Vora A, Bonney D, Veys P, Rao K, Lucchini G, Chiesa R, Chu J, Clark L, Fung MM, Smith K, Peticone C, Al-Hajj M, Baldan V, Ferrari M, Srivastava S, Jha R, Arce Vargas F, Duffy K, Day W, Virgo P, Wheeler L, Hancock J, Farzaneh F, Domning S, Zhang Y, Khokhar NZ, Peddareddigari VGR, Wynn R, Pule M, Amrolia PJ. Cordoba S, et al. Nat Med. 2021 Oct;27(10):1797-1805. doi: 10.1038/s41591-021-01497-1. Epub 2021 Oct 12. Nat Med. 2021. PMID: 34642489 Free PMC article. Clinical Trial.
Tunable control of CAR T cell activity through tetracycline mediated disruption of protein-protein interaction.
Hotblack A, Kokalaki EK, Palton MJ, Cheung GW, Williams IP, Manzoor S, Grothier TI, Piapi A, Fiaccadori V, Wawrzyniecka P, Roddy HA, Agliardi G, Roddie C, Onuoha S, Thomas S, Cordoba S, Pule M. Hotblack A, et al. Among authors: cordoba s. Sci Rep. 2021 Nov 9;11(1):21902. doi: 10.1038/s41598-021-01418-9. Sci Rep. 2021. PMID: 34754016 Free PMC article.
A compact and simple method of achieving differential transgene expression by exploiting translational readthrough.
Sillibourne JE, Agliardi G, Righi M, Smetanova K, Rowley G, Speller S, Dolor A, Lamb K, Allen C, Karattil R, Parekh F, Vargas FA, Thomas S, Cordoba S, Pule M. Sillibourne JE, et al. Among authors: cordoba s. Biotechniques. 2022 Apr;72(4):143-154. doi: 10.2144/btn-2021-0079. Epub 2022 Mar 2. Biotechniques. 2022. PMID: 35234525 Free article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: cordoba s. Mol Ther. 2023 Jul 5;31(7):2089-2104. doi: 10.1016/j.ymthe.2023.03.020. Epub 2023 Mar 21. Mol Ther. 2023. PMID: 36945773 Free article.
Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy.
Lee L, Lim WC, Galas-Filipowicz D, Fung K, Taylor J, Patel D, Akbar Z, Alvarez Mediavilla E, Wawrzyniecka P, Shome D, Reijmers RM, Gregg T, Wood L, Day W, Cerec V, Ferrari M, Thomas S, Cordoba S, Onuoha S, Khokhar N, Peddareddigari V, Al-Hajj M, Cavet J, Zweegman S, Rodriguez-Justo M, Youg K, Pule M, Popat R. Lee L, et al. Among authors: cordoba s. J Immunother Cancer. 2023 Jun;11(6):e006699. doi: 10.1136/jitc-2023-006699. J Immunother Cancer. 2023. PMID: 37399355 Free PMC article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: cordoba s. Mol Ther. 2024 Feb 7;32(2):556-558. doi: 10.1016/j.ymthe.2023.12.006. Epub 2023 Dec 15. Mol Ther. 2024. PMID: 38103549 Free article. No abstract available.
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction.
Jha R, Kinna A, Hotblack A, Bughda R, Bulek A, Gannon I, Ilca T, Allen C, Lamb K, Dolor A, Scott I, Parekh F, Sillibourne J, Cordoba S, Onuoha S, Thomas S, Ferrari M, Pule M. Jha R, et al. Among authors: cordoba s. ACS Chem Biol. 2024 Feb 16;19(2):308-324. doi: 10.1021/acschembio.3c00521. Epub 2024 Jan 20. ACS Chem Biol. 2024. PMID: 38243811 Free PMC article.
237 results