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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.
Sanders BC, Pokhrel S, Labbe AD, Mathews II, Cooper CJ, Davidson RB, Phillips G, Weiss KL, Zhang Q, O'Neill H, Kaur M, Schmidt JG, Reichard W, Surendranathan S, Parvathareddy J, Phillips L, Rainville C, Sterner DE, Kumaran D, Andi B, Babnigg G, Moriarty NW, Adams PD, Joachimiak A, Hurst BL, Kumar S, Butt TR, Jonsson CB, Ferrins L, Wakatsuki S, Galanie S, Head MS, Parks JM. Sanders BC, et al. Among authors: cooper cj. Nat Commun. 2023 Mar 28;14(1):1733. doi: 10.1038/s41467-023-37254-w. Nat Commun. 2023. PMID: 36977673 Free PMC article.
Targeted isolation and cultivation of uncultivated bacteria by reverse genomics.
Cross KL, Campbell JH, Balachandran M, Campbell AG, Cooper CJ, Griffen A, Heaton M, Joshi S, Klingeman D, Leys E, Yang Z, Parks JM, Podar M. Cross KL, et al. Among authors: cooper cj. Nat Biotechnol. 2019 Nov;37(11):1314-1321. doi: 10.1038/s41587-019-0260-6. Epub 2019 Sep 30. Nat Biotechnol. 2019. PMID: 31570900 Free PMC article.
Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold.
Green AT, Moniruzzaman M, Cooper CJ, Walker JK, Smith JC, Parks JM, Zgurskaya HI. Green AT, et al. Among authors: cooper cj. Biochim Biophys Acta Gen Subj. 2020 Jun;1864(6):129546. doi: 10.1016/j.bbagen.2020.129546. Epub 2020 Feb 4. Biochim Biophys Acta Gen Subj. 2020. PMID: 32032658 Free PMC article.
β-Barrel proteins tether the outer membrane in many Gram-negative bacteria.
Sandoz KM, Moore RA, Beare PA, Patel AV, Smith RE, Bern M, Hwang H, Cooper CJ, Priola SA, Parks JM, Gumbart JC, Mesnage S, Heinzen RA. Sandoz KM, et al. Among authors: cooper cj. Nat Microbiol. 2021 Jan;6(1):19-26. doi: 10.1038/s41564-020-00798-4. Epub 2020 Nov 2. Nat Microbiol. 2021. PMID: 33139883 Free PMC article.
229 results