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FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M. Doll S, et al. Among authors: conrad m. Nature. 2019 Nov;575(7784):693-698. doi: 10.1038/s41586-019-1707-0. Epub 2019 Oct 21. Nature. 2019. PMID: 31634899
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Rådmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Förster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M. Friedmann Angeli JP, et al. Among authors: conrad m. Nat Cell Biol. 2014 Dec;16(12):1180-91. doi: 10.1038/ncb3064. Epub 2014 Nov 17. Nat Cell Biol. 2014. PMID: 25402683 Free PMC article.
ROS, thiols and thiol-regulating systems in male gametogenesis.
Conrad M, Ingold I, Buday K, Kobayashi S, Angeli JP. Conrad M, et al. Biochim Biophys Acta. 2015 Aug;1850(8):1566-74. doi: 10.1016/j.bbagen.2014.10.020. Epub 2014 Oct 23. Biochim Biophys Acta. 2015. PMID: 25450170 Review.
Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation.
Kagan VE, Tyurina YY, Tyurin VA, Mohammadyani D, Angeli JP, Baranov SV, Klein-Seetharaman J, Friedlander RM, Mallampalli RK, Conrad M, Bayir H. Kagan VE, et al. Among authors: conrad m. Antioxid Redox Signal. 2015 Jun 20;22(18):1667-80. doi: 10.1089/ars.2014.6219. Epub 2015 Mar 31. Antioxid Redox Signal. 2015. PMID: 25566681 Free PMC article. Review.
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Hellfritsch J, Kirsch J, Schneider M, Fluege T, Wortmann M, Frijhoff J, Dagnell M, Fey T, Esposito I, Kölle P, Pogoda K, Angeli JP, Ingold I, Kuhlencordt P, Östman A, Pohl U, Conrad M, Beck H. Hellfritsch J, et al. Among authors: conrad m. Antioxid Redox Signal. 2015 Apr 10;22(11):938-50. doi: 10.1089/ars.2014.5889. Antioxid Redox Signal. 2015. PMID: 25647640 Free PMC article.
The antioxidant requirement for plasma membrane repair in skeletal muscle.
Labazi M, McNeil AK, Kurtz T, Lee TC, Pegg RB, Angeli JPF, Conrad M, McNeil PL. Labazi M, et al. Among authors: conrad m. Free Radic Biol Med. 2015 Jul;84:246-253. doi: 10.1016/j.freeradbiomed.2015.03.016. Epub 2015 Apr 3. Free Radic Biol Med. 2015. PMID: 25843658 Free PMC article.
Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility.
Ingold I, Aichler M, Yefremova E, Roveri A, Buday K, Doll S, Tasdemir A, Hoffard N, Wurst W, Walch A, Ursini F, Friedmann Angeli JP, Conrad M. Ingold I, et al. Among authors: conrad m. J Biol Chem. 2015 Jun 5;290(23):14668-78. doi: 10.1074/jbc.M115.656363. Epub 2015 Apr 28. J Biol Chem. 2015. PMID: 25922076 Free PMC article.
1,306 results