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144 results

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Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.
Ozmadenci D, Shankara Narayanan JS, Andrew J, Ojalill M, Barrie AM, Jiang S, Iyer S, Chen XL, Rose M, Estrada V, Molinolo A, Bertotto T, Mikulski Z, McHale MC, White RR, Connolly DC, Pachter JA, Kuchroo VK, Stupack DG, Schlaepfer DD. Ozmadenci D, et al. Among authors: connolly dc. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2117065119. doi: 10.1073/pnas.2117065119. Epub 2022 Apr 25. Proc Natl Acad Sci U S A. 2022. PMID: 35467979 Free PMC article.
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Győrffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. Diaz Osterman CJ, et al. Among authors: connolly dc. Elife. 2019 Sep 3;8:e47327. doi: 10.7554/eLife.47327. Elife. 2019. PMID: 31478830 Free PMC article.
Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.
Kleinschmidt EG, Miller NLG, Ozmadenci D, Tancioni I, Osterman CD, Barrie AM, Taylor KN, Ye A, Jiang S, Connolly DC, Stupack DG, Schlaepfer DD. Kleinschmidt EG, et al. Among authors: connolly dc. Oncogene. 2019 Sep;38(36):6323-6337. doi: 10.1038/s41388-019-0881-8. Epub 2019 Jul 15. Oncogene. 2019. PMID: 31308489 Free PMC article.
Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion.
Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC. Do TV, et al. Among authors: connolly dc. Oncogene. 2014 Jan 30;33(5):539-49. doi: 10.1038/onc.2012.632. Epub 2013 Jan 21. Oncogene. 2014. PMID: 23334327 Free PMC article.
Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.
Pieretti-Vanmarcke R, Donahoe PK, Pearsall LA, Dinulescu DM, Connolly DC, Halpern EF, Seiden MV, MacLaughlin DT. Pieretti-Vanmarcke R, et al. Among authors: connolly dc. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17426-31. doi: 10.1073/pnas.0607959103. Epub 2006 Nov 6. Proc Natl Acad Sci U S A. 2006. PMID: 17088539 Free PMC article.
Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype.
Cvrljevic AN, Butt U, Huhtinen K, Grönroos TJ, Böckelman C, Lassus H, Butzow R, Haglund C, Kaipio K, Arsiola T, Laajala TD, Connolly DC, Ristimäki A, Carpen O, Pouwels J, Westermarck J. Cvrljevic AN, et al. Among authors: connolly dc. Mol Cancer Ther. 2022 Jul 5;21(7):1236-1245. doi: 10.1158/1535-7163.MCT-21-0622. Mol Cancer Ther. 2022. PMID: 35364610 Free PMC article.
NEDD9 promotes oncogenic signaling in mammary tumor development.
Izumchenko E, Singh MK, Plotnikova OV, Tikhmyanova N, Little JL, Serebriiskii IG, Seo S, Kurokawa M, Egleston BL, Klein-Szanto A, Pugacheva EN, Hardy RR, Wolfson M, Connolly DC, Golemis EA. Izumchenko E, et al. Among authors: connolly dc. Cancer Res. 2009 Sep 15;69(18):7198-206. doi: 10.1158/0008-5472.CAN-09-0795. Epub 2009 Sep 8. Cancer Res. 2009. PMID: 19738060 Free PMC article.
Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.
Kurimchak AM, Herrera-Montávez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Kurimchak AM, et al. Among authors: connolly dc. Sci Signal. 2020 Feb 18;13(619):eaax8238. doi: 10.1126/scisignal.aax8238. Sci Signal. 2020. PMID: 32071169 Free PMC article.
144 results