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Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, Gottesdiener A, Bounds R, Sharma S, Folster C, Henderson B, O'Rahilly S, Stoner E, Gottesdiener K, Panaro BL, Cone RD, Clément K, Farooqi IS, Van der Ploeg LHT. Collet TH, et al. Among authors: cone rd. Mol Metab. 2017 Oct;6(10):1321-1329. doi: 10.1016/j.molmet.2017.06.015. Epub 2017 Jul 8. Mol Metab. 2017. PMID: 29031731 Free PMC article. Clinical Trial.
Activation of central melanocortin pathways by fenfluramine.
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Heisler LK, et al. Among authors: cone rd. Science. 2002 Jul 26;297(5581):609-11. doi: 10.1126/science.1072327. Science. 2002. PMID: 12142539
Physiological roles of the melanocortin MC₃ receptor.
Renquist BJ, Lippert RN, Sebag JA, Ellacott KL, Cone RD. Renquist BJ, et al. Among authors: cone rd. Eur J Pharmacol. 2011 Jun 11;660(1):13-20. doi: 10.1016/j.ejphar.2010.12.025. Epub 2011 Jan 3. Eur J Pharmacol. 2011. PMID: 21211527 Free PMC article. Review.
Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery.
Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM. Hatoum IJ, et al. Among authors: cone rd. J Clin Endocrinol Metab. 2012 Jun;97(6):E1023-31. doi: 10.1210/jc.2011-3432. Epub 2012 Apr 6. J Clin Endocrinol Metab. 2012. PMID: 22492873 Free PMC article.
Melanocortin-3 receptor regulates the normal fasting response.
Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD. Renquist BJ, et al. Among authors: cone rd. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1489-98. doi: 10.1073/pnas.1201994109. Epub 2012 May 9. Proc Natl Acad Sci U S A. 2012. PMID: 22573815 Free PMC article.
192 results