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Structure activity relationship of dendrimer microbicides with dual action antiviral activity.
Tyssen D, Henderson SA, Johnson A, Sterjovski J, Moore K, La J, Zanin M, Sonza S, Karellas P, Giannis MP, Krippner G, Wesselingh S, McCarthy T, Gorry PR, Ramsland PA, Cone R, Paull JR, Lewis GR, Tachedjian G. Tyssen D, et al. Among authors: cone r. PLoS One. 2010 Aug 23;5(8):e12309. doi: 10.1371/journal.pone.0012309. PLoS One. 2010. PMID: 20808791 Free PMC article.
Vaginal concentrations of lactic acid potently inactivate HIV.
Aldunate M, Tyssen D, Johnson A, Zakir T, Sonza S, Moench T, Cone R, Tachedjian G. Aldunate M, et al. Among authors: cone r. J Antimicrob Chemother. 2013 Sep;68(9):2015-25. doi: 10.1093/jac/dkt156. Epub 2013 May 8. J Antimicrob Chemother. 2013. PMID: 23657804 Free PMC article.
Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.
Tyssen D, Wang YY, Hayward JA, Agius PA, DeLong K, Aldunate M, Ravel J, Moench TR, Cone RA, Tachedjian G. Tyssen D, et al. Among authors: cone ra. mSphere. 2018 Jul 5;3(4):e00055-18. doi: 10.1128/mSphere.00055-18. mSphere. 2018. PMID: 29976641 Free PMC article.
Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition.
Hearps AC, Tyssen D, Srbinovski D, Bayigga L, Diaz DJD, Aldunate M, Cone RA, Gugasyan R, Anderson DJ, Tachedjian G. Hearps AC, et al. Among authors: cone ra. Mucosal Immunol. 2017 Nov;10(6):1480-1490. doi: 10.1038/mi.2017.27. Epub 2017 Apr 12. Mucosal Immunol. 2017. PMID: 28401934 Free article.
Drug-induced reactivation of apoptosis abrogates HIV-1 infection.
Hanauske-Abel HM, Saxena D, Palumbo PE, Hanauske AR, Luchessi AD, Cambiaghi TD, Hoque M, Spino M, D'Alliessi Gandolfi D, Heller DS, Singh S, Park MH, Cracchiolo BM, Tricta F, Connelly J, Popowicz AM, Cone RA, Holland B, Pe'ery T, Mathews MB. Hanauske-Abel HM, et al. PLoS One. 2013 Sep 23;8(9):e74414. doi: 10.1371/journal.pone.0074414. eCollection 2013. PLoS One. 2013. PMID: 24086341 Free PMC article.
609 results