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DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells.
Cueto FJ, Del Fresno C, Brandi P, Combes AJ, Hernández-García E, Sánchez-Paulete AR, Enamorado M, Bromley CP, Gomez MJ, Conde-Garrosa R, Mañes S, Zelenay S, Melero I, Iborra S, Krummel MF, Sancho D. Cueto FJ, et al. Among authors: combes aj. J Immunother Cancer. 2021 May;9(5):e002054. doi: 10.1136/jitc-2020-002054. J Immunother Cancer. 2021. PMID: 33980589 Free PMC article.
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. Barry KC, et al. Among authors: combes aj. Nat Med. 2018 Aug;24(8):1178-1191. doi: 10.1038/s41591-018-0085-8. Epub 2018 Jun 25. Nat Med. 2018. PMID: 29942093 Free PMC article.
Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity.
Binnewies M, Mujal AM, Pollack JL, Combes AJ, Hardison EA, Barry KC, Tsui J, Ruhland MK, Kersten K, Abushawish MA, Spasic M, Giurintano JP, Chan V, Daud AI, Ha P, Ye CJ, Roberts EW, Krummel MF. Binnewies M, et al. Among authors: combes aj. Cell. 2019 Apr 18;177(3):556-571.e16. doi: 10.1016/j.cell.2019.02.005. Epub 2019 Apr 4. Cell. 2019. PMID: 30955881 Free PMC article.
Lessons of COVID-19: A roadmap for post-pandemic science.
Freedman TS, Headley MB, Serwas N, Ruhland M, Castellanos CA, Combes AJ, Krummel MF. Freedman TS, et al. Among authors: combes aj. J Exp Med. 2020 Sep 7;217(9):e20201276. doi: 10.1084/jem.20201276. J Exp Med. 2020. PMID: 32735669 Free PMC article.
Global Absence and Targeting of Protective Immune States in Severe COVID-19.
Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S; UCSF COMET Consortium; Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. Combes AJ, et al. Res Sq [Preprint]. 2020 Oct 28:rs.3.rs-97042. doi: 10.21203/rs.3.rs-97042/v1. Res Sq. 2020. PMID: 33140041 Free PMC article. Updated. Preprint.
SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution.
Argüello RJ, Combes AJ, Char R, Gigan JP, Baaziz AI, Bousiquot E, Camosseto V, Samad B, Tsui J, Yan P, Boissonneau S, Figarella-Branger D, Gatti E, Tabouret E, Krummel MF, Pierre P. Argüello RJ, et al. Among authors: combes aj. Cell Metab. 2020 Dec 1;32(6):1063-1075.e7. doi: 10.1016/j.cmet.2020.11.007. Cell Metab. 2020. PMID: 33264598 Free PMC article.
A tumor-specific mechanism of Treg enrichment mediated by the integrin αvβ8.
Seed RI, Kobayashi K, Ito S, Takasaka N, Cormier A, Jespersen JM, Publicover J, Trilok S, Combes AJ, Chew NW, Chapman J, Krummel MF, Lou J, Marks J, Cheng Y, Baron JL, Nishimura SL. Seed RI, et al. Among authors: combes aj. Sci Immunol. 2021 Mar 26;6(57):eabf0558. doi: 10.1126/sciimmunol.abf0558. Sci Immunol. 2021. PMID: 33771888 Free PMC article.
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.
van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ; UCSF COMET consortium. van der Wijst MGP, et al. Among authors: combes aj. Sci Transl Med. 2021 Sep 22;13(612):eabh2624. doi: 10.1126/scitranslmed.abh2624. Epub 2021 Aug 24. Sci Transl Med. 2021. PMID: 34429372 Free PMC article.
Archetypes of checkpoint-responsive immunity.
Im K, Combes AJ, Spitzer MH, Satpathy AT, Krummel MF. Im K, et al. Among authors: combes aj. Trends Immunol. 2021 Nov;42(11):960-974. doi: 10.1016/j.it.2021.09.007. Epub 2021 Oct 9. Trends Immunol. 2021. PMID: 34642094 Free PMC article. Review.
66 results