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The protein histidine phosphatase LHPP is a tumour suppressor.
Hindupur SK, Colombi M, Fuhs SR, Matter MS, Guri Y, Adam K, Cornu M, Piscuoglio S, Ng CKY, Betz C, Liko D, Quagliata L, Moes S, Jenoe P, Terracciano LM, Heim MH, Hunter T, Hall MN. Hindupur SK, et al. Among authors: colombi m. Nature. 2018 Mar 29;555(7698):678-682. doi: 10.1038/nature26140. Epub 2018 Mar 21. Nature. 2018. PMID: 29562234 Free PMC article.
Syrosingopine sensitizes cancer cells to killing by metformin.
Benjamin D, Colombi M, Hindupur SK, Betz C, Lane HA, El-Shemerly MY, Lu M, Quagliata L, Terracciano L, Moes S, Sharpe T, Wodnar-Filipowicz A, Moroni C, Hall MN. Benjamin D, et al. Among authors: colombi m. Sci Adv. 2016 Dec 23;2(12):e1601756. doi: 10.1126/sciadv.1601756. eCollection 2016 Dec. Sci Adv. 2016. PMID: 28028542 Free PMC article.
mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Guri Y, Colombi M, Dazert E, Hindupur SK, Roszik J, Moes S, Jenoe P, Heim MH, Riezman I, Riezman H, Hall MN. Guri Y, et al. Among authors: colombi m. Cancer Cell. 2017 Dec 11;32(6):807-823.e12. doi: 10.1016/j.ccell.2017.11.011. Cancer Cell. 2017. PMID: 29232555 Free article.
Insulin resistance causes inflammation in adipose tissue.
Shimobayashi M, Albert V, Woelnerhanssen B, Frei IC, Weissenberger D, Meyer-Gerspach AC, Clement N, Moes S, Colombi M, Meier JA, Swierczynska MM, Jenö P, Beglinger C, Peterli R, Hall MN. Shimobayashi M, et al. Among authors: colombi m. J Clin Invest. 2018 Apr 2;128(4):1538-1550. doi: 10.1172/JCI96139. Epub 2018 Mar 12. J Clin Invest. 2018. PMID: 29528335 Free PMC article.
285 results