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Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators. Heier JS, et al. Lancet. 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. Lancet. 2023. PMID: 37865470 Clinical Trial.
How can global guidelines support sustainable hygiene systems?
Esteves Mills J, Thomas A, Abdalla N, El-Alam R, Al-Shabi K, Ashinyo ME, Bangoura FO, Charles K, Chipungu J, Cole AO, Engebretson B, Goyol K, Grasham CF, Grossi V, Hickling S, Kalandarov S, Ababu AK, Kholmuhammad K, Klaesener-Metzner N, Kugedera Z, Kwakye A, Lee-Llacer A, Maani PP, Makhafola B, Mohamed A, Monirul Alam M, Monse B, Northover H, Palomares A, Patabendi N, Paynter N, Prasad-Gautam O, Panthi SR, Rudge L, Saha S, Salaru I, Saltiel G, Sax L, Shahid MA, Gafur MS, Shrestha S, Szeberényi K, Tidwell JB, Trinies V, Yiha O, Ziganshin R, Gordon B, Cumming O. Esteves Mills J, et al. Among authors: cole ao. BMJ Glob Health. 2023 Oct;8(10):e013632. doi: 10.1136/bmjgh-2023-013632. BMJ Glob Health. 2023. PMID: 37879652 Free PMC article. No abstract available.
Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies.
Hodgson SH, Douglas AD, Edwards NJ, Kimani D, Elias SC, Chang M, Daza G, Seilie AM, Magiri C, Muia A, Juma EA, Cole AO, Rampling TW, Anagnostou NA, Gilbert SC, Hoffman SL, Draper SJ, Bejon P, Ogutu B, Marsh K, Hill AV, Murphy SC. Hodgson SH, et al. Among authors: cole ao. Malar J. 2015 Jan 28;14:33. doi: 10.1186/s12936-015-0541-6. Malar J. 2015. PMID: 25627033 Free PMC article.
Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.
Hodgson SH, Juma E, Salim A, Magiri C, Kimani D, Njenga D, Muia A, Cole AO, Ogwang C, Awuondo K, Lowe B, Munene M, Billingsley PF, James ER, Gunasekera A, Sim BK, Njuguna P, Rampling TW, Richman A, Abebe Y, Kamuyu G, Muthui M, Elias SC, Molyneux S, Gerry S, Macharia A, Williams TN, Bull PC, Hill AV, Osier FH, Draper SJ, Bejon P, Hoffman SL, Ogutu B, Marsh K. Hodgson SH, et al. Among authors: cole ao. Front Microbiol. 2014 Dec 12;5:686. doi: 10.3389/fmicb.2014.00686. eCollection 2014. Front Microbiol. 2014. PMID: 25566206 Free PMC article.