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Rational-Based Discovery of Novel β-Carboline Derivatives as Potential Antimalarials: From In Silico Identification of Novel Targets to Inhibition of Experimental Cerebral Malaria.
Alves FM, Bellei JCB, Barbosa CS, Duarte CL, Fonseca ALD, Pinto ACS, Raimundo FO, Carpinter BA, Lemos ASO, Coimbra ES, Taranto AG, Rocha VN, de Pilla Varotti F, Ribeiro Viana GH, Scopel KKG. Alves FM, et al. Among authors: coimbra es. Pathogens. 2022 Dec 13;11(12):1529. doi: 10.3390/pathogens11121529. Pathogens. 2022. PMID: 36558863 Free PMC article.
Biomphalaria spp. (Preston,1910) snails in the municipality of Juiz de Fora, Zona da Mata Mineira mesoregion, state of Minas Gerais, Brazil.
Tibiriçá SH, Bessa EC, Mittherofhe A, Castro MF, Carvalho Odos S, Caldeira RL, Passos LK, Mattos AM, Pinheiro LS, Sacramento e Silva D, Bastos FO, Andreoli GQ, Bonato GR, Coimbra ES. Tibiriçá SH, et al. Among authors: coimbra es. Mem Inst Oswaldo Cruz. 2006 Sep;101 Suppl 1:179-84. doi: 10.1590/s0074-02762006000900028. Mem Inst Oswaldo Cruz. 2006. PMID: 17308767 Free article.
Evidence of Leishmania (Leishmania) infantum infection in dogs from Juiz de Fora, Minas Gerais State, Brazil, based on immunochromatographic dual-path platform (DPP®) and PCR assays.
Castro-Júnior JG, Freire ML, Campos SP, Scopel KK, Porrozzi R, Da Silva ED, Colombo FA, da Silveira Rde C, Marques MJ, Coimbra ES. Castro-Júnior JG, et al. Among authors: coimbra es. Rev Inst Med Trop Sao Paulo. 2014 May-Jun;56(3):225-9. doi: 10.1590/s0036-46652014000300008. Rev Inst Med Trop Sao Paulo. 2014. PMID: 24879001 Free PMC article.
A simple quinoline salt derivative is active in vitro against Plasmodiumfalciparum asexual blood stages and inhibits the development of cerebral malaria in murine model.
Bezerra Bellei JC, Glanzmann N, Carpinter BA, Renhe DC, Marques CB, Azevedo MR, Barreto LM, Rocha VN, Karine da Costa Nunes I, Gualberto Pereira HM, Coimbra ES, Ferraz Coelho EA, David da Silva A, de Pilla Varotti F, Gorza Scopel KK. Bezerra Bellei JC, et al. Among authors: coimbra es. Chem Biol Interact. 2022 Mar 1;355:109848. doi: 10.1016/j.cbi.2022.109848. Epub 2022 Feb 9. Chem Biol Interact. 2022. PMID: 35149084
92 results