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Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.
Chuckran CA, Cillo AR, Moskovitz J, Overacre-Delgoffe A, Somasundaram AS, Shan F, Magnon GC, Kunning SR, Abecassis I, Zureikat AH, Luketich J, Pennathur A, Sembrat J, Rojas M, Merrick DT, Taylor SE, Orr B, Modugno F, Buckanovich R, Schoen RE, Kim S, Duvvuri U, Zeh H, Edwards R, Kirkwood JM, Coffman L, Ferris RL, Bruno TC, Vignali DAA. Chuckran CA, et al. Among authors: coffman l. Sci Transl Med. 2021 Dec 8;13(623):eabf8495. doi: 10.1126/scitranslmed.abf8495. Epub 2021 Dec 8. Sci Transl Med. 2021. PMID: 34878821 Free PMC article.
The double edge sword of fibrosis in cancer.
Chandler C, Liu T, Buckanovich R, Coffman LG. Chandler C, et al. Transl Res. 2019 Jul;209:55-67. doi: 10.1016/j.trsl.2019.02.006. Epub 2019 Feb 21. Transl Res. 2019. PMID: 30871956 Free PMC article. Review.
Mesenchymal Stem Cells in the Tumor Microenvironment.
Atiya H, Frisbie L, Pressimone C, Coffman L. Atiya H, et al. Among authors: coffman l. Adv Exp Med Biol. 2020;1234:31-42. doi: 10.1007/978-3-030-37184-5_3. Adv Exp Med Biol. 2020. PMID: 32040853 Review.
Phase II clinical trial of metformin as a cancer stem cell-targeting agent in ovarian cancer.
Brown JR, Chan DK, Shank JJ, Griffith KA, Fan H, Szulawski R, Yang K, Reynolds RK, Johnston C, McLean K, Uppal S, Liu JR, Cabrera L, Taylor SE, Orr BC, Modugno F, Mehta P, Bregenzer M, Mehta G, Shen H, Coffman LG, Buckanovich RJ. Brown JR, et al. Among authors: coffman lg. JCI Insight. 2020 Jun 4;5(11):e133247. doi: 10.1172/jci.insight.133247. JCI Insight. 2020. PMID: 32369446 Free PMC article. Clinical Trial.
B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma.
Ruffin AT, Cillo AR, Tabib T, Liu A, Onkar S, Kunning SR, Lampenfeld C, Atiya HI, Abecassis I, Kürten CHL, Qi Z, Soose R, Duvvuri U, Kim S, Oesterrich S, Lafyatis R, Coffman LG, Ferris RL, Vignali DAA, Bruno TC. Ruffin AT, et al. Among authors: coffman lg. Nat Commun. 2021 Jun 7;12(1):3349. doi: 10.1038/s41467-021-23355-x. Nat Commun. 2021. PMID: 34099645 Free PMC article.
Phase I trial of ribociclib with platinum chemotherapy in ovarian cancer.
Coffman LG, Orellana TJ, Liu T, Frisbie LG, Normolle D, Griffith K, Uppal S, McLean K, Berger J, Boisen M, Courtney-Brooks M, Edwards RP, Lesnock J, Mahdi H, Olawaiye A, Sukumvanich P, Taylor SE, Buckanovich R. Coffman LG, et al. JCI Insight. 2022 Sep 22;7(18):e160573. doi: 10.1172/jci.insight.160573. JCI Insight. 2022. PMID: 35972817 Free PMC article. Clinical Trial.
64 results