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Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.
Zentner I, Sierra LJ, Maciunas L, Vinnik A, Fedichev P, Mankowski MK, Ptak RG, Martín-García J, Cocklin S. Zentner I, et al. Among authors: cocklin s. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1132-5. doi: 10.1016/j.bmcl.2012.11.041. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23305922 Free PMC article.
Identification of a small-molecule inhibitor of HIV-1 assembly that targets the phosphatidylinositol (4,5)-bisphosphate binding site of the HIV-1 matrix protein.
Zentner I, Sierra LJ, Fraser AK, Maciunas L, Mankowski MK, Vinnik A, Fedichev P, Ptak RG, Martín-García J, Cocklin S. Zentner I, et al. Among authors: cocklin s. ChemMedChem. 2013 Mar;8(3):426-32. doi: 10.1002/cmdc.201200577. Epub 2013 Jan 29. ChemMedChem. 2013. PMID: 23361947 Free PMC article.
Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.
Sun L, Huang T, Dick A, Meuser ME, Zalloum WA, Chen CH, Ding X, Gao P, Cocklin S, Lee KH, Zhan P, Liu X. Sun L, et al. Among authors: cocklin s. Eur J Med Chem. 2020 Mar 15;190:112085. doi: 10.1016/j.ejmech.2020.112085. Epub 2020 Jan 24. Eur J Med Chem. 2020. PMID: 32066010 Free PMC article.
82 results