Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies.
Méplan C, Johnson IT, Polley AC, Cockell S, Bradburn DM, Commane DM, Arasaradnam RP, Mulholland F, Zupanic A, Mathers JC, Hesketh J.
Méplan C, et al. Among authors: cockell s.
FASEB J. 2016 Aug;30(8):2812-25. doi: 10.1096/fj.201600251R. Epub 2016 Apr 21.
FASEB J. 2016.
PMID: 27103578
This is the first study combining omics technologies to describe the impact of differences in Se status on colorectal expression patterns, revealing that suboptimal Se status could alter inflammatory signaling and cytoskeleton in human rectal mucosa and so influence cancer risk.- …
This is the first study combining omics technologies to describe the impact of differences in Se status on colorectal expression patterns, r …