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PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma.
Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, Cloughesy T, Lai A, Phillips HS, Marshall R, Mueller S, Haas-Kogan DA, Molinaro AM, Perry A. Phillips JJ, et al. Among authors: cloughesy t. Brain Pathol. 2013 Sep;23(5):565-73. doi: 10.1111/bpa.12043. Epub 2013 Mar 18. Brain Pathol. 2013. PMID: 23438035 Free PMC article.
Prognostic significance of growth kinetics in newly diagnosed glioblastomas revealed by combining serial imaging with a novel biomathematical model.
Wang CH, Rockhill JK, Mrugala M, Peacock DL, Lai A, Jusenius K, Wardlaw JM, Cloughesy T, Spence AM, Rockne R, Alvord EC Jr, Swanson KR. Wang CH, et al. Among authors: cloughesy t. Cancer Res. 2009 Dec 1;69(23):9133-40. doi: 10.1158/0008-5472.CAN-08-3863. Epub 2009 Nov 24. Cancer Res. 2009. PMID: 19934335 Free PMC article.
Genomic landscape of meningiomas.
Lee Y, Liu J, Patel S, Cloughesy T, Lai A, Farooqi H, Seligson D, Dong J, Liau L, Becker D, Mischel P, Shams S, Nelson S. Lee Y, et al. Among authors: cloughesy t. Brain Pathol. 2010 Jul;20(4):751-62. doi: 10.1111/j.1750-3639.2009.00356.x. Epub 2009 Nov 20. Brain Pathol. 2010. PMID: 20015288 Free PMC article.
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme.
Lai A, Tran A, Nghiemphu PL, Pope WB, Solis OE, Selch M, Filka E, Yong WH, Mischel PS, Liau LM, Phuphanich S, Black K, Peak S, Green RM, Spier CE, Kolevska T, Polikoff J, Fehrenbacher L, Elashoff R, Cloughesy T. Lai A, et al. Among authors: cloughesy t. J Clin Oncol. 2011 Jan 10;29(2):142-8. doi: 10.1200/JCO.2010.30.2729. Epub 2010 Dec 6. J Clin Oncol. 2011. PMID: 21135282 Free PMC article. Clinical Trial.
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang Z, Aldape KD, Mischel PS, Liau LM, Escovedo CJ, Chen W, Nghiemphu PL, James CD, Prados MD, Westphal M, Lamszus K, Cloughesy T, Phillips HS. Lai A, et al. Among authors: cloughesy t. J Clin Oncol. 2011 Dec 1;29(34):4482-90. doi: 10.1200/JCO.2010.33.8715. Epub 2011 Oct 24. J Clin Oncol. 2011. PMID: 22025148 Free PMC article.
Bevacizumab as first-line therapy for glioblastoma.
Piccioni D, Lai A, Nghiemphu P, Cloughesy T. Piccioni D, et al. Among authors: cloughesy t. Future Oncol. 2012 Aug;8(8):929-38. doi: 10.2217/fon.12.81. Future Oncol. 2012. PMID: 22894667
Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.
Chou AP, Chowdhury R, Li S, Chen W, Kim AJ, Piccioni DE, Selfridge JM, Mody RR, Chang S, Lalezari S, Lin J, Sanchez DE, Wilson RW, Garrett MC, Harry B, Mottahedeh J, Nghiemphu PL, Kornblum HI, Mischel PS, Prins RM, Yong WH, Cloughesy T, Nelson SF, Liau LM, Lai A. Chou AP, et al. Among authors: cloughesy t. J Natl Cancer Inst. 2012 Oct 3;104(19):1458-69. doi: 10.1093/jnci/djs357. Epub 2012 Sep 3. J Natl Cancer Inst. 2012. PMID: 22945948 Free PMC article.
469 results