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The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.
Benci K, Wittine K, Radan M, Cetina M, Sedić M, Kraljević Pavelić S, Pavelić K, Clercq ED, Mintas M. Benci K, et al. Among authors: clercq ed. Bioorg Med Chem. 2010 Sep 1;18(17):6249-57. doi: 10.1016/j.bmc.2010.07.035. Epub 2010 Aug 7. Bioorg Med Chem. 2010. PMID: 20696582
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
Baraldi PG, Balboni G, Pavani MG, Spalluto G, Tabrizi MA, Clercq ED, Balzarini J, Bando T, Sugiyama H, Romagnoli R. Baraldi PG, et al. Among authors: clercq ed. J Med Chem. 2001 Aug 2;44(16):2536-43. doi: 10.1021/jm0108404. J Med Chem. 2001. PMID: 11472207
46 results