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Obesity and melanoma: could fat be fueling malignancy?
Clement E, Lazar I, Muller C, Nieto L. Clement E, et al. Pigment Cell Melanoma Res. 2017 May;30(3):294-306. doi: 10.1111/pcmr.12584. Epub 2017 Apr 20. Pigment Cell Melanoma Res. 2017. PMID: 28222242 Review.
Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.
Lazar I, Clement E, Dauvillier S, Milhas D, Ducoux-Petit M, LeGonidec S, Moro C, Soldan V, Dalle S, Balor S, Golzio M, Burlet-Schiltz O, Valet P, Muller C, Nieto L. Lazar I, et al. Among authors: clement e. Cancer Res. 2016 Jul 15;76(14):4051-7. doi: 10.1158/0008-5472.CAN-16-0651. Epub 2016 May 23. Cancer Res. 2016. PMID: 27216185
Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress.
Laurent V, Toulet A, Attané C, Milhas D, Dauvillier S, Zaidi F, Clement E, Cinato M, Le Gonidec S, Guérard A, Lehuédé C, Garandeau D, Nieto L, Renaud-Gabardos E, Prats AC, Valet P, Malavaud B, Muller C. Laurent V, et al. Among authors: clement e. Mol Cancer Res. 2019 Mar;17(3):821-835. doi: 10.1158/1541-7786.MCR-18-0748. Epub 2019 Jan 3. Mol Cancer Res. 2019. PMID: 30606769
Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP).
Lehuédé C, Li X, Dauvillier S, Vaysse C, Franchet C, Clement E, Esteve D, Longué M, Chaltiel L, Le Gonidec S, Lazar I, Geneste A, Dumontet C, Valet P, Nieto L, Fallone F, Muller C. Lehuédé C, et al. Among authors: clement e. Breast Cancer Res. 2019 Jan 17;21(1):7. doi: 10.1186/s13058-018-1088-6. Breast Cancer Res. 2019. PMID: 30654824 Free PMC article.
Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells.
Clement E, Lazar I, Attané C, Carrié L, Dauvillier S, Ducoux-Petit M, Esteve D, Menneteau T, Moutahir M, Le Gonidec S, Dalle S, Valet P, Burlet-Schiltz O, Muller C, Nieto L. Clement E, et al. EMBO J. 2020 Feb 3;39(3):e102525. doi: 10.15252/embj.2019102525. Epub 2020 Jan 10. EMBO J. 2020. PMID: 31919869 Free PMC article.
Human adipocyte function is impacted by mechanical cues.
Pellegrinelli V, Heuvingh J, du Roure O, Rouault C, Devulder A, Klein C, Lacasa M, Clément E, Lacasa D, Clément K. Pellegrinelli V, et al. Among authors: clement e, clement k. J Pathol. 2014 Jun;233(2):183-95. doi: 10.1002/path.4347. J Pathol. 2014. PMID: 24623048
539 results