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A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. Reddy K, et al. Among authors: cleary jd. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20991-21000. doi: 10.1073/pnas.1901893116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570586 Free PMC article.
Drug Screen Tugs at Common Thread for Repeat Disorders.
Reddy K, Cleary JD, Berglund JA. Reddy K, et al. Among authors: cleary jd. Trends Pharmacol Sci. 2020 Feb;41(2):71-73. doi: 10.1016/j.tips.2019.12.004. Epub 2020 Jan 8. Trends Pharmacol Sci. 2020. PMID: 31926601
Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening.
Jenquin JR, O'Brien AP, Poukalov K, Lu Y, Frias JA, Shorrock HK, Richardson JI, Mazdiyasni H, Yang H, Huigens RW 3rd, Boykin D, Ranum LPW, Cleary JD, Wang ET, Berglund JA. Jenquin JR, et al. Among authors: cleary jd. iScience. 2022 Apr 4;25(5):104198. doi: 10.1016/j.isci.2022.104198. eCollection 2022 May 20. iScience. 2022. PMID: 35479399 Free PMC article.
Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9.
Pinto BS, Saxena T, Oliveira R, Méndez-Gómez HR, Cleary JD, Denes LT, McConnell O, Arboleda J, Xia G, Swanson MS, Wang ET. Pinto BS, et al. Among authors: cleary jd. Mol Cell. 2017 Nov 2;68(3):479-490.e5. doi: 10.1016/j.molcel.2017.09.033. Epub 2017 Oct 19. Mol Cell. 2017. PMID: 29056323 Free PMC article.
Intron retention induced by microsatellite expansions as a disease biomarker.
Sznajder ŁJ, Thomas JD, Carrell EM, Reid T, McFarland KN, Cleary JD, Oliveira R, Nutter CA, Bhatt K, Sobczak K, Ashizawa T, Thornton CA, Ranum LPW, Swanson MS. Sznajder ŁJ, et al. Among authors: cleary jd. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4234-4239. doi: 10.1073/pnas.1716617115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610297 Free PMC article.
Repeat-associated non-ATG (RAN) translation.
Cleary JD, Pattamatta A, Ranum LPW. Cleary JD, et al. J Biol Chem. 2018 Oct 19;293(42):16127-16141. doi: 10.1074/jbc.R118.003237. Epub 2018 Sep 13. J Biol Chem. 2018. PMID: 30213863 Free PMC article.
122 results