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GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao Y, Du Jiang P, Chao BN, Cagdas D, Kubo S, Balasubramaniyam A, Zhang Y, Shadur B, NaserEddin A, Folio LR, Schwarz B, Bohrnsen E, Zheng L, Lynberg M, Gottlieb S, Leney-Greene MA, Park AY, Tezcan I, Akdogan A, Gocmen R, Onder S, Rosenberg A, Soilleux EJ, Johnson E, Jackson PK, Demeter J, Chauvin SD, Paul F, Selbach M, Bulut H, Clatworthy MR, Tuong ZK, Zhang H, Stewart BJ, Bosio CM, Stepensky P, Clare S, Ganesan S, Pascall JC, Daumke O, Butcher GW, McMichael AJ, Simon AK, Lenardo MJ. Yao Y, et al. Among authors: clatworthy mr. J Exp Med. 2022 Jun 6;219(6):e20201405. doi: 10.1084/jem.20201405. Epub 2022 May 13. J Exp Med. 2022. PMID: 35551368 Free PMC article.
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR. Castro-Dopico T, et al. Among authors: clatworthy mr. Immunity. 2019 Apr 16;50(4):1099-1114.e10. doi: 10.1016/j.immuni.2019.02.006. Epub 2019 Mar 12. Immunity. 2019. PMID: 30876876 Free PMC article.
Organ immune responses - don't forget the structural cells.
Tuong ZK, Clatworthy MR. Tuong ZK, et al. Among authors: clatworthy mr. Nat Rev Nephrol. 2020 Oct;16(10):570-571. doi: 10.1038/s41581-020-00334-x. Nat Rev Nephrol. 2020. PMID: 32792669 No abstract available.
Gut-educated IgA plasma cells defend the meningeal venous sinuses.
Fitzpatrick Z, Frazer G, Ferro A, Clare S, Bouladoux N, Ferdinand J, Tuong ZK, Negro-Demontel ML, Kumar N, Suchanek O, Tajsic T, Harcourt K, Scott K, Bashford-Rogers R, Helmy A, Reich DS, Belkaid Y, Lawley TD, McGavern DB, Clatworthy MR. Fitzpatrick Z, et al. Among authors: clatworthy mr. Nature. 2020 Nov;587(7834):472-476. doi: 10.1038/s41586-020-2886-4. Epub 2020 Nov 4. Nature. 2020. PMID: 33149302 Free PMC article.
A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia.
Tuong ZK, Lukowski SW, Nguyen QH, Chandra J, Zhou C, Gillinder K, Bashaw AA, Ferdinand JR, Stewart BJ, Teoh SM, Hanson SJ, Devitt K, Clatworthy MR, Powell JE, Frazer IH. Tuong ZK, et al. Among authors: clatworthy mr. iScience. 2021 Oct 21;24(11):103326. doi: 10.1016/j.isci.2021.103326. eCollection 2021 Nov 19. iScience. 2021. PMID: 34805788 Free PMC article.
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Mulderrig L, et al. Among authors: clatworthy mr. Nature. 2021 Dec;600(7887):158-163. doi: 10.1038/s41586-021-04133-7. Epub 2021 Nov 24. Nature. 2021. PMID: 34819667
159 results