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MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE. Dovey CM, et al. Among authors: clarke bp. Mol Cell. 2018 Jun 7;70(5):936-948.e7. doi: 10.1016/j.molcel.2018.05.010. Epub 2018 Jun 7. Mol Cell. 2018. PMID: 29883610 Free PMC article.
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
Xie Y, Gao S, Zhang K, Bhat P, Clarke BP, Batten K, Mei M, Gazzara M, Shay JW, Lynch KW, Angelos AE, Hill PS, Ivey AL, Fontoura BMA, Ren Y. Xie Y, et al. Among authors: clarke bp. Cell Rep. 2023 Aug 29;42(8):112988. doi: 10.1016/j.celrep.2023.112988. Epub 2023 Aug 14. Cell Rep. 2023. PMID: 37578863 Free PMC article.
Cryo-EM structure of the CBC-ALYREF complex.
Clarke BP, Angelos AE, Mei M, Hill PS, Xie Y, Ren Y. Clarke BP, et al. bioRxiv [Preprint]. 2023 Oct 2:2023.10.01.559959. doi: 10.1101/2023.10.01.559959. bioRxiv. 2023. PMID: 37873070 Free PMC article. Preprint.
Holographic free-electron light source.
Li G, Clarke BP, So JK, MacDonald KF, Zheludev NI. Li G, et al. Among authors: clarke bp. Nat Commun. 2016 Dec 2;7:13705. doi: 10.1038/ncomms13705. Nat Commun. 2016. PMID: 27910853 Free PMC article.
Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.
Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Ward SE, et al. Among authors: clarke bp. J Med Chem. 2011 Jan 13;54(1):78-94. doi: 10.1021/jm100679e. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128618
Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor.
Concha NO, Janson CA, Rowling P, Pearson S, Cheever CA, Clarke BP, Lewis C, Galleni M, Frère JM, Payne DJ, Bateson JH, Abdel-Meguid SS. Concha NO, et al. Among authors: clarke bp. Biochemistry. 2000 Apr 18;39(15):4288-98. doi: 10.1021/bi992569m. Biochemistry. 2000. PMID: 10757977
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