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Hepatitis E virus infects brain microvascular endothelial cells, crosses the blood-brain barrier, and invades the central nervous system.
Tian D, Li W, Heffron CL, Wang B, Mahsoub HM, Sooryanarain H, Hassebroek AM, Clark-Deener S, LeRoith T, Meng XJ. Tian D, et al. Among authors: clark deener s. Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2201862119. doi: 10.1073/pnas.2201862119. Epub 2022 Jun 7. Proc Natl Acad Sci U S A. 2022. PMID: 35671427 Free PMC article.
Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity.
Cao D, Cao QM, Subramaniam S, Yugo DM, Heffron CL, Rogers AJ, Kenney SP, Tian D, Matzinger SR, Overend C, Catanzaro N, LeRoith T, Wang H, Piñeyro P, Lindstrom N, Clark-Deener S, Yuan L, Meng XJ. Cao D, et al. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):6914-6923. doi: 10.1073/pnas.1705446114. Epub 2017 Jun 19. Proc Natl Acad Sci U S A. 2017. PMID: 28630341 Free PMC article.
Virus-like particle vaccine with B-cell epitope from porcine epidemic diarrhea virus (PEDV) incorporated into hepatitis B virus core capsid provides clinical alleviation against PEDV in neonatal piglets through lactogenic immunity.
Lu Y, Clark-Deener S, Gillam F, Heffron CL, Tian D, Sooryanarain H, LeRoith T, Zoghby J, Henshaw M, Waldrop S, Pittman J, Meng XJ, Zhang C. Lu Y, et al. Among authors: clark deener s. Vaccine. 2020 Jul 14;38(33):5212-5218. doi: 10.1016/j.vaccine.2020.06.009. Epub 2020 Jun 19. Vaccine. 2020. PMID: 32565343
21 results