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Helminth Immunomodulation in Autoimmune Disease.
Smallwood TB, Giacomin PR, Loukas A, Mulvenna JP, Clark RJ, Miles JJ. Smallwood TB, et al. Among authors: clark rj. Front Immunol. 2017 Apr 24;8:453. doi: 10.3389/fimmu.2017.00453. eCollection 2017. Front Immunol. 2017. PMID: 28484453 Free PMC article. Review.
Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.
Miles JJ, Tan MP, Dolton G, Edwards ES, Galloway SA, Laugel B, Clement M, Makinde J, Ladell K, Matthews KK, Watkins TS, Tungatt K, Wong Y, Lee HS, Clark RJ, Pentier JM, Attaf M, Lissina A, Ager A, Gallimore A, Rizkallah PJ, Gras S, Rossjohn J, Burrows SR, Cole DK, Price DA, Sewell AK. Miles JJ, et al. Among authors: clark rj. J Clin Invest. 2018 Apr 2;128(4):1569-1580. doi: 10.1172/JCI91512. Epub 2018 Mar 12. J Clin Invest. 2018. PMID: 29528337 Free PMC article.
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations.
Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: clark rj. Toxins (Basel). 2021 Feb 14;13(2):146. doi: 10.3390/toxins13020146. Toxins (Basel). 2021. PMID: 33672955 Free PMC article.
Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo.
Smallwood TB, Navarro S, Cristofori-Armstrong B, Watkins TS, Tungatt K, Ryan RYM, Haigh OL, Lutzky VP, Mulvenna JP, Rosengren KJ, Loukas A, Miles JJ, Clark RJ. Smallwood TB, et al. Among authors: clark rj. J Biol Chem. 2021 Jul;297(1):100834. doi: 10.1016/j.jbc.2021.100834. Epub 2021 May 27. J Biol Chem. 2021. PMID: 34051231 Free PMC article.
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: clark rj. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
The "C3aR Antagonist" SB290157 is a Partial C5aR2 Agonist.
Li XX, Kumar V, Clark RJ, Lee JD, Woodruff TM. Li XX, et al. Among authors: clark rj. Front Pharmacol. 2021 Jan 21;11:591398. doi: 10.3389/fphar.2020.591398. eCollection 2020. Front Pharmacol. 2021. PMID: 33551801 Free PMC article.
Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.
Croker DE, Monk PN, Halai R, Kaeslin G, Schofield Z, Wu MC, Clark RJ, Blaskovich MA, Morikis D, Floudas CA, Cooper MA, Woodruff TM. Croker DE, et al. Among authors: clark rj. Immunol Cell Biol. 2016 Sep;94(8):787-95. doi: 10.1038/icb.2016.43. Epub 2016 Apr 25. Immunol Cell Biol. 2016. PMID: 27108698 Free article.
315 results